Transient hypogammaglobulinemia of infancy (THI) is originally defined as a physiological maturation defect of immunoglobulin G (IgG) production that occurs at 3-6 months of age and lasts until 18 to 36 months of age. We report here on a 22-month-old child with THI and IgA deficiency, who had massive pneumococcal empyema. Her depressed IgG level returned to normal within 6 months, but IgA level...

Background: Neonatal period is defined as up to first 28 days of life and further divided into very early (birth <24 h), <7 days), late neonatal (7 <28 days). the most vulnerable human it accounts for high morbidities mortalities these are preventable. India contributes one-fifth global live births more than a quarter deaths. Respiratory distress common cause NICU admission Aim current...

Hypoglycemia is the most common metabolic alteration in neonatal period. Most of these neonates have transient hypoglycemia. However, persistent and recurrent hypoglycemia in neonates is usually caused by endocrine or metabolic disorders. These babies require frequent glucose monitoring to prevent hypoglycemic brain injury and advanced investigations for diagnosis of underlying etiology. An app...

BACKGROUND Infections by a variety of pathogens are a significant cause of morbidity and mortality during perinatal period. The susceptibility of neonates to bacterial infections has been attributed to immaturity of innate immunity. It is considered that one of the impaired mechanisms is the phagocytic function of neutrophils and monocytes. The purpose of the present study was to investigate th...

Ten pregnant Norway rats (Rattus norvegicus) were flown for 11 days on board the NASA space shuttle from gestational day 9 (launch) until gestational day 20 (landing) of the rats' 22-day pregnancy. After the birth of the pups, vestibular responses were analyzed from postnatal day (P) 0 until P5. In the first test, P0 neonates were supported on a platform in a side-lying position. Skyward head m...

UNLABELLED Hyperbilirubinemia is toxic to the auditory pathways and to the central nervous system, leaving sequelae such as hearing loss and encephalopathy. AIM to assess the hearing of neonates with hyperbilirubinemia, using transient evoked otoacoustic emissions (TOAEs) and brainstem evoked auditory potentials (BEAP). Prospective study. MATERIALS AND METHODS we had two groups: GI (n-25), ...