Evolutionary changes in transcriptional regulation undoubtedly play an important role in creating morphological diversity. However, there is little information about the evolutionary dynamics of cis-regulatory sequences. This study examines the functional consequence of evolutionary changes in the Endo16 promoter of sea urchins. The Endo16 gene encodes a large extracellular protein that is expr...

SIGNIFICANCE Environmental and endogenous reactive species such as reactive oxygen species (ROS), reactive nitrogen species (RNS), and other electrophiles are not only known to exert toxic effects on organisms, but are also emerging as molecules that mediate cell signaling responses. However, the mechanisms underlying this cellular redox signaling by reactive species remains largely uncharacter...

the study of the exclosure effects on the vegetation changes undergrazing and non-grazing conditions in the rangeland areas has particularimportance in the rangeland improvement and revivification projects. theresearch was accomplished in semi-steppe khoybilehvar area, from 1999 to2005. vegetation cover was annually measured within fixed plots during transact.the results showed that during nine...

this paper presents a method for diagnosis of eccentricity fault in a switched-reluctance motor (srm) during offline and standstill modes. in this method, the fault signature is differential induced voltage (div) achieved by injecting diagnostic pulses to the motor windings. it will be demonstrated by means of results that there is a correlation between differential induced voltage and eccentri...

conclusions the pattern of longitudinally increased liver stiffness measurements efficiently supported clinical decisions for individualized management strategies. repeated transient elastography in real-life clinical practice appears to have a practical role in monitoring liver transplanted patients. background liver transplanted patients need close surveillance for early signs of graft diseas...

introduction: the main purpose of this study was to compare transient ischemic dilation (tid) ratios in spect-low dose ct and spect myocardial perfusion imaging (mpi) by application of different quantitative programs and quantify the possible shift in the upper normal limits of tid ratio in the spect-ct mpi. methods: 149 patients with low pre-test probability for coronary artery disease (cad),...

a novel method to compute the stability region in power system transient stability analysis is presented. this method is based on the set analysis. the key to this method is to construct the hamilton-jacobi-isaacs (hji) partial differential equation (pde) of a nonlinear system, using which we can compute the backward reachable set by applying the level set methods. the backward reachable set of...

introduction: transient cavitations induced by low frequency irradiation of ultrasound can be used to treat tumors. previous studies in in-vitro experiments have shown that induced cavitation by dual or multiple frequencies of ultrasound is greater than induced cavitation by single frequency irradiation. in this study, we compared and evaluated the treatment effects of dual frequency irradiatio...

introduction: acoustic transient cavitation is the primary mechanism of sonochemical reaction and has potential use for tumor treatment. in this study, the in vivo anti-tumor effect of simultaneous dual-frequency ultrasound at low-level intensity (isata < 6 w/cm2) was investigated in a spontaneous murine model of breast adenocarcinoma in balb/c mice. materials and methods: forty tumor bearing m...

Many biological macromolecular interactions proceed via lowly-populated, highly transient species that arise from rare excursions between the minimum free energy configuration and other local minima of the free energy landscape. Little is known about the structural properties of such lowly-occupied states since they are difficult to trap and hence inaccessible to conventional structural and bio...