OBJECTIVE To evaluate the results of T4, TSH analysis and pattern of presentation in babies born at our hospital. METHOD We retrospectively reviewed the data collected from T4, TSH screening on all babies delivered at our Hospital, where the blood was drawn within the first 4 days of life. Period under evaluation was from October 1995 to October 1998. Shifa Reference values were used. RESUL...

Skin disinfection with povidine-iodine (PVP-I) is widely used in obstetrics. We evaluated the influence of PVP-I in mothers at delivery on the serum thyroid stimulating hormone concentrations of their infants at the time of screening for congenital hypothyroidism. The study covered 4745 infants who were either breast fed (3659, 77%) or bottle fed (1086, 23%); 3086 (65%) of them were born to mot...

conclusions high tc, tg and vldl were observed in our patients with sch. objectives the aim of this study was to assess differences in lipid profile parameters between subjects with and without sch in a north indian population. patients and methods serum lipid parameters of 70 patients with subclinical hypothyroidism and 100 age and sex matched euthyroid controls were evaluated in a cross-secti...

Hypothyroidism is one of the most common endocrine diseases. More than 99% all cases hypothyroidism in adults are due to primary hypothyroidism. Most often, develops because chronic autoimmune thyroiditis, as well after medical manipulations (iatrogenic hypothyroidism) — postoperative or a result therapy with radioactive iodine. The article presents draft clinical guidelines for diagnosis and t...

Hashimoto's thyroiditis (HT) is part of the spectrum of autoimmune thyroid diseases. Clinical manifestations of HT are variable and commonly include diffuse or nodular goiter with euthyroidism, subclinical hypothyroidism and permanent hypothyroidism. Uncommonly, HT causes acute destruction of thyroid tissue and release of stored thyroid hormones, causing transient thyrotoxicosis (hashitoxicosis...

Most of our knowledge on the mechanisms of thyroid hormone (TH) dependent brain development is based on clinical observations and animal studies of maternal/fetal hypothyroidism. THs play an essential role in brain development and hormone deficiency during critical phases in fetal life may lead to severe and permanent brain damage. Maternal hypothyroidism is considered the most common cause of ...

BACKGROUND Williams-Beuren syndrome (WBS, OMIM-194050) is a neurodevelopmental disorder with multisystemic manifestations caused by a 1.55-1.83 Mb deletion at 7q11.23 including 26-28 genes. Reported endocrine and metabolic abnormalities include transient hypercalcaemia of infancy, subclinical hypothyroidism in ∼ 30% of children and impaired glucose tolerance in ∼ 75% of adult individuals. The p...

Thyroid hormone is essential for mammalian brain development, but the mechanisms by which thyroid hormone exerts its effects, the developmental processes affected, and the timing of thyroid hormone effects are poorly understood. An important question is whether thyroid hormone of maternal origin is essential in guiding fetal brain development. In both humans and rats, thyroid hormone of materna...

Abstract Introduction: Hypothyroidism usually affects red blood cell line most commonly seen as normochromic normocytic anemia. We present a unique case of patient with pancytopenia in the setting severe hypothyroidism, which improved following IV thyroid hormone replacement. Case: An 85-year-old female history type II diabetes mellitus and hypothyroidism who was admitted for open reduction int...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : many patients using warfarin may be at risk of international normalized ratio fluctuations. this may cause severe massive gastrointestinal or cerebral bleeding. subclinical hypothyroidism in our population is highly prevalent (range from 3.1% to 8.4% for males and females respectively). overt hypothyroidism di...