Phytomedicines are used worldwide by human being from ancient times. Herbal drugs are becoming more popular in the modern world for their application to cure variety of diseases with less toxic effects and better therapeutic effects. However these medicines suffer from certain limitation such as toxicity, stability issues, poor bioavailability and patient compliance. To minimize these problems ...

Drug loaded dissolving microneedles (DMNs) fabricated with water soluble polymers have received increasing attentions as a safe and efficient transdermal drug delivery system. Usually, to reach a high drug delivery efficiency, an ideal drug distribution is gathering more drugs in the tip or the top part of DMNs. In this work, we introduce an easy and new method to introduce a bubble with contro...

Transdermal medication delivery systems provide systemic therapy by passive diffusion through the skin. They offer an alternative route of medication administration and may be well suited for patients who are unable to take or retain oral medications. Granisetron transdermal system (Sancuso(R), ProStrakan, Inc.) is the first transdermal medication patch indicated for the prevention of nausea an...

Background and objective: Applying liposomal gels in transdermal drug delivery system has evoked considerable interest because of their good activity for osteoarthritis. The aim present study was to prepare characterize liposomes NSAIDS meloxicam, which may deliver these drugs the target site more efficiently also overcome problem related with oral drug. Methodology: In investigation efficiency...

Transdermal drug delivery systems (TDDS) are used to deliver the drug(s) or therapeutically active substances through topical route primarily skin. Relatively very small numbers of drugs administered transdermally because in many cases physical properties drugs, including polarity and molecular size, have limited its capacity particular dug transdermally. Now a day’s transdermal techniques vari...

The modern era has witnessed development of alternate and successful routes of drug delivery system i.e. Transdermal Drug Delivery System (TDDS). In a broad sense, it includes all topically administered drug formulations intended to deliver the active ingredient into the general circulation. Increasing prevalence of diabetes is presently pushing strong demand for novel drug delivery devices. Mo...

The paper focuses on the advances in the field of pain treatment by transdermal delivery of specific drugs. Starting from a short description of the skin barrier, the pharmacodynamics and pharmacokinetics including absorption, distribution, action mechanism, metabolism and toxicity, aspects related to the use of pain therapy drugs are further discussed. Most recent results on topical anesthetic...