We herein describe a systematic account of mononuclear ruthenium vinyl complexes L-{Ru}-CH=CH-R where the phosphine ligands at the (PR'3)2Ru(CO)Cl={Ru} moiety, the coordination number at the metal (L = 4-ethylisonicotinate or a vacant coordination site) and the substituent R (R = nbutyl, phenyl, 1-pyrenyl) have been varied. Structures of the enynyl complex Ru(CO)Cl(PPh3)2(eta1:eta2-nBuHC=CHCCnB...

has been studied and the formation of acrolein as a product confirmed by gas chromatography-mass spectrometry. Oxi dation of 4-methylcyclophosphamide generates methyl vinyl ketone. This is interpreted to indicate that the acrolein and methyl vinyl ketone arise from oxidation of position 4 of the ring of cyclophosphamide. The Fenton oxidation of both cyclophosphamide and 4-methylcylophosphamide ...

Cross-metathesis of α- and β-vinyl C-deoxyribosides and α-vinyl C-galactoside with various terminal alkenes under different conditions was studied. The cross-metathesis of the former proceeded with good yields of the corresponding products in ClCH2CH2Cl the latter required the presence of CuI in CH2Cl2 to achieve good yields of the products. A simple method for the preparation of α- and β-vinyl...

The copper-catalyzed diboration of ketones followed by an acid-catalyzed elimination leads to the formation of 1,1-disubstituted and trisubstituted vinyl boronate esters with moderate to good yields and selectivity. Addition of tosic acid to the crude diboration products provides the corresponding vinyl boronate esters upon elimination. The trisubstituted vinyl boronate esters are formed as the...

A facile I2O5-mediated direct oxidative coupling of aromatic alkenes with thiols toward vinyl sulfones has been developed under metal-free conditions. This methodology provides a convenient and efficient approach to various (E)-vinyl sulfones from readily available starting materials with excellent regioselectivity. The present oxidative coupling reaction, not only expands the scope of function...

Objective(s): Newer organo-metallic, specifically gold (III) complexes with multiple ligands are currently being formulated with primary focus of having increased anti-cancerous properties and decreased cytotoxicity. In this study, histological toxicity profile of a newly formulated anti-cancerous gold (III) compound [trans-(±)-1,2-(DACH)2Au]Cl3 Bis(trans-1,2-Diaminocyclohexane) was investigate...

Magnetic polymer particles which were modified by vinyl groups and subjected topolymerization by vinyl β-Cyclodextrin derivative, has been used as adsorbent for sorption andrelease of bovine serum albumin and the equilibrium and kinetics of the adsorption process werestudied. The absorbability and releasing of this protein through the new polymer has beenmeasured by ultraviolet-visible spectros...

A stereodivergent coupling reaction between vinyl halides and boronic esters is described. This coupling process proceeds without a transition-metal catalyst, instead proceeding by electrophilic selenation or iodination of a vinyl boronate complex followed by stereospecific syn or anti elimination. Chiral, nonracemic boronic esters could be coupled with complete enantiospecificity. The process ...