نتایج جستجو برای: toxicity risk factors
تعداد نتایج: 1856550 فیلتر نتایج به سال:
P310 Toxicity of thiopurines in patients with inflammatory bowel disease: Frequency and risk factors
Although ICIs revolutionized modern oncology, a significant challenge remains to minimize immune related adverse events (irAEs), and subsequent financial burden due treatment delay hospitalization. There is paucity of data about predicting biomarkers for ICI-related toxicity. In this study we aimed use machine learning (ML) algorithms the profile ICI A computer algorithm was developed using SAP...
Background and Objective: This study conducted to assess ecological risk of an important group of pollutants called polycyclic aromatic hydrocarbons (PAHs) in offshore sediment of the Persian Gulf deposits in Bushehr province. The aim of this study was to model the toxicity of PAHs for aquatic organisms in the study area. Materials and Methods: In the first step of the applied risk assessment ...
Nearly 50% of cancer patients undergo radiotherapy. Late radiotherapy toxicity affects quality-of-life in long-term cancer survivors and risk of side-effects in a minority limits doses prescribed to the majority of patients. Development of a test predicting risk of toxicity could benefit many cancer patients. We aimed to meta-analyze individual level data from four genome-wide association studi...
AIMS In cervical cancer patients with intermediate-risk factors, the optimal adjuvant therapy is still controversial. We retrospectively compared the treatment outcome of chemoradiation with that of radiation. METHODS From 1997 to 2005, 79 consecutive cervical cancer patients received postoperative adjuvant therapy indicated by intermediate-risk factors. Fifty-five women received chemoradiati...
Infants and children are not little adults. They are uniquely vulnerable to environmental toxicants. To protect infants and children against toxicants, the National Research Council in 1993 called for development of an approach to risk assessment that considers children's unique patterns of exposure and their special vulnerabilities to pesticides. Many aspects of that call were codified into fe...
Acute kidney injury (AKI) is a growing problem with untoward economic and medical consequences. Anticancer drug toxicity remains an important and increasing cause of AKI. Importantly, drug-induced AKI affects all nephron segments-vasculature, glomerulus, tubules, and interstitium. Recent studies have increased insight into the subcellular mechanisms of drug-induced AKI that include direct cellu...
In the environment, organisms are exposed to a diverse array of chemicals in complexmixtures. Themajority of approaches that aim to assess the risk of environmental chemical mixtures, including those used by regulatory bodies, use toxicity data generated from the individual component chemicals to predict the overall mixture toxicity. It is assumed that the behaviour of chemicals in a mixture ca...
introduction all nations are striving for development. economic development is one of the main parts of development process, but not all of it. populations health is one of the main factors of economic development, and child’s mortality is one of the main factors of population health status. the aim of this study is investigating the role of socioeconomic disparties in under 5 mortality in east...
conclusions in this study, the prevalence of hcv was 0.2%, which is lower than the mean prevalence in iran (1%). prevalence of hcv had a significant relationship with iv-drug abuse. results the mean age of the participants was 39.7 ± 14.4. among them, 52.2% were female and 29.9% had university degrees. prevalence of hcv-ab+ was about 0.2% with elisa, and 0.14% of entire group were confirmed by ...
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