PURPOSE The report of two cases of ischemic optic neuropathy after hip and shoulder arthroplasty under general anesthesia. One of them is the first reported posterior ischemic optic neuropathy after shoulder surgery up to our knowledge. METHODS Case reports and review of the literature reporting also data of the anesthesia period. RESULTS The first case is a 74-year-old male patient with po...

OBJECTIVES To determine whether early recognition and detection of thrombocytosis in patients with giant cell arteritis can help secure an earlier diagnosis, and whether it can help differentiate cases of arteritic optic neuropathy from other forms of optic neuropathy. METHODS Medical and ophthalmologic records from 1993 to 1998 of the authors' patients with biopsy-proven temporal arteritis v...

A patient undergoing chemotherapy for treatment of acute lymphocytic leukemia developed septicemia that was treated with linezolid for 16 days. The patient subsequently reported reduced vision in both eyes and was found to have bilateral optic neuropathy. After the discontinuation of linezolid treatment, both the optic neuropathy and visual impairment resolved without sequelae.

BACKGROUND Patients on linezolid-containing drug-resistant TB (DR-TB) regimen often develop adverse-events, particularly peripheral and optic neuropathy. Programmatic data and experiences of linezolid-associated optic neuropathy from high DR-TB burden settings are lacking. The study aimed to determine the frequency of and risk-factors associated with linezolid-associated optic neuropathy and do...

purpose : to evaluate the effects of memantine on improving visual function in patients with acute nonarteritic anterior ischemic optic neuropathy (naion) methods : this was a prospective, double masked, randomized, clinical trial. the study involved 47 subjects with unilateral naion of less than 8 weeks duration. eligible patients were randomly allocated to take either memantine tablets (5 mg ...

purpose : evaluation of efficacy of memantine (n-methyl-d-aspartate receptor antagonist) on visual function of patients with acute non-arteritic ischemic optic neuropathy (naion). methods : the study was conducted as interventional case series from november 2005 through november 2006 in farabi eye hospital . twenty-two patients with acute naion of less than 8 weeks duration entered the study. m...

background: sleep apnea is temporary cessation or absence of breathing during sleep. significant increase in blood pressure is clinically seen in apneic episodes. the aim of this study was to examine sleep apnea syndrome as a risk factor for non- arthritic anterior ischemic optic neuropathy (naion) in a case control study. methods: nineteen naion patients (9 men and 10 women) and 31 age and sex...

InTRoDUCTIon Inflammatory, demyelinating optic neuritis is one of the most common optic neuropathies in young adults. It occurs idiopathically, or in association with multiple sclerosis, and follows a typical course of progressing visual dysfunction often with pain for one – two weeks, followed by significant resolution over the next few weeks. Due to the characteristic presentation and frequen...

Although the transcription factor, nuclear factor survival, its precise role in cell death within the central nervous system (CNS) remains unknown. previously reported that mice with a homozygous deficiency for NF optic neuropathy. We examined the expression and activation of pro mediate optic neuropathy in p50 known to regulate the recombination of immunoglobulin V(D)J. Experiments with gene e...