The application of inorganic chemistry to medicine (“Elemental Medicine”) is a rapidly developing field, and novel therapeutic and diagnostic metal complexes are now having an impact on medical practice. Advances in biocoordination chemistry are crucial for improving the design of compounds to reduce toxic side-effects and understand their mechanisms of action. In this article, we focus on the ...

Given the presence of toxic metals in some local Iranian as well as some imported rice varieties, it may be of help to focus on public awareness for the implementation of educational interventions. This study aimed to assess awareness and attitudes of women in Sanandaj, Iran, regarding toxic metal-contaminated rice based on the Health Belief Model (HBM). This cross-sectional study was conducted...

The Cu(II), Fe(II), Mn(II) and Zn(II) metal complexes of Schiff base 2-(salicylimino)-3-hydroxypyridine (SIHP) were prepared and characterized by various analytical techniques such as FTIR, UV-Visible spectroscopy and elemental analyses. The magnetic moment values suggested octahedral geometry for these transition metal complexes. Thermal stability of the compounds synthesized was also studied....

The successful design of orally active non-toxic selective metal chelators is a much sought-after goal. In order to identify an ideal chelator for clinical use, a range of specifications must be considered, such as metal selectivity and affinity, kinetic stability of the complex, bioavailability and toxicity. In this overview the comparative properties of ligands capable of endowing complexes w...

Most drugs used today are purely organic compounds. Especially after the enormous success of the cisplatin (Fig 1) in tumor treatment, interest in metal complexes has grown (Allardyce & Dyson, 2006). Synthetic organometallic compounds are generally considered to be toxic or non-compatible with biological systems. Despite this perception, the medicinal properties of organometallic compounds, in ...

objective: zayandehrood habitat has economical and environmental importance in central plateau of iran    and it performs a vital role for habitants, agriculture section and the industries which are located along river bed. so current research  has been done to measure the contamination of heavy metals, its changes along the river route and defining the important and effective regions on this c...

Proliferation of toxic cyanobacteria in waterways is a significant global problem. Environmental stressors, including metal toxicity, can affect algal growth and metabolism. There is a need to understand the influence of environmental stressors on the formation and regulation of both cyanobacterial blooms and toxin production. This review will investigate the effects of metal stressors on cyano...

Certain heavy metals such as mercury, lead, arsenic and cadmium are toxic even in reduced concentrations in blood. Their accumulation in the body causes serious illnesses. The most important heavy metals in human pathology are: mercury (Hg), cadmium (Cd), arsenic (As) and lead (Pb). The author mentions the heavy metal sources of poisoning, their toxicokinetics and toxicodynamics, clinical featu...

Metal ions are essential for growth, but in excess, these compounds can become highly toxic. Both plants and animals have adapted numerous ways to maintain metal homeostasis while mitigating detrimental effects of excess metals ions, including the metalchelating proteins metallothionein (MT) and phytochelatin. Although phytochelatins have been shown to play an important role in the detoxificati...

: heavy metals are chemical pollutants characterized by their toxicity, stability, bioaccumulation and biomagnification. they might accumulate in aquatic organisms, transfer through food chain and enter into human body. therefore, the study of their accumulation in the edible aquatic species has been a very important part of ecological and monitoring investigations. astacus leptodactylus is a b...