Background Using our method for selectively detecting the response of intratumor quiescent (Q) cells to irradiation, the Q cells was shown to have a much larger hypoxic fraction (HF) than total (= proliferating (P) + Q) tumor cell population irrespective of the p53 status of tumor cells. However, the size of the HF was clearly less than 100%, meaning the Q cell population was never fully hypoxi...

objective(s): the aim of this study was to determine whether high-dose radioactive iodine (na131i) outpatient treatment of patients with thyroid carcinoma is a pragmatically safe approach, particularly for the safety of caregivers. methods: a total of 79 patients completed the radiation-safety questionnaires prior to receiving high-dose radioactive iodine treatment. the questionnaire studied th...

  Introduction: Radioactive materials deliver internal radiation dose to patients in nuclear medicine. Manual internal radiation dose assessment is a complicated method. Introduction of a simple dose calculation software is the main goal of the present study. Methods: Using the best current data in internal dose calculation (S-Factors) recommended by ICRP and by cons...

Cardiovascular disease is the major cause of mortality in patients receiving hemodialysis for chronic renal failure. Increased lipid peroxidation and depletion of chain-breaking antioxidants may contribute to increased risk of atherosclerosis. We have therefore assessed the effect of a single episode of hemodialysis on antioxidant status in 22 patients and control subjects. Overall, total antio...

Ultraviolet B (UVB) irradiation can cause human skin damage or aging and wrinkle formation through photochemical reactions. Antioxidative substances may ameliorate UV damage. In this study, the anti-photoaging activity of three antioxidants—ergothioneine, ferulic acid, glutathione—was investigated after UVB Hs68 fibroblast cells. The cells treated with these antioxidants appeared similar to uni...

Introduction:   Radiotherapy with or without surgery plays an important role in the treatment of patients with esophageal cancer. In the treatment planning of esophageal cancer, usually normal lung volume was observed in the treatment fields and probably received high radiation dose. The incidence of radiation pneumonitis (RP) after radiotherapy (RT) for sensitive organ of lu...

Background: Exposure to ionizing radiation results in genotoxicity and the unrepaired lesions in cellular DNA results in cell cycle arrest, reproductive death, interphase death, division delay, chromosome aberrations, mutations, etc. leading to the intensive destruction of cells and violation of their proliferative capacity there by adversely affecting the mammalian system. Since ionizing radia...

BACKGROUND A better understanding of the pathophysiology of ischaemia-reperfusion injury and a possible treatment for it, is of great importance. The deep inferior epigastric perforator (DIEP) flap is an innovative, clinical model of ischaemia-reperfusion. There has been an ongoing interest in the health benefits and medical applications of antioxidants. We hypothesised that during ischaemia-re...

background: natural radiation is constantly present in the environment and is emitted from a variety of natural and artificial sources. it affects human body and environment. materials and methods: the activity concentrations of 238u, 232th and 40k have been determined by gamma ray spectrometer with an hpge detector in sediments of cauvery river, tamilnadu, india. results: the absorbed dose rat...