\ The records of our criminal jurisprudence are fertile in instances in which the most atrocious crimes are perpetrated 1^ persons who are absolved from responsibility on the ground of insanity. The mind is horrified at the tale of a mother cutting the throats of her helpless infants as they lie slumbering in their beds, or of another parent hurrying away her progeny in the darkness of the nigh...

An agent may decide to delegate tasks to others. The act of delegating a task by one autonomous agent to another can be carried out by the performance of one or more imperative communication acts. In this paper, the semantics of imperatives are specified using a language of actions and states. It is further shown how the model can be used to distinguish between whole-hearted and mere extensiona...

Actual-sequence views of responsibility are views according to which moral responsibility is a function of actual sequences, histories, or ancestries. In recent years these views have acquired much popularity as an attractive kind of compatibilist answer to the problem of determinism and the freedom of the will. But what does it mean to say that responsibility is ‘a function of the actual seque...

How do people attribute responsibility in situations where the contributions of multiple agents combine to produce a joint outcome? The prevalence of over-determination in such cases makes this a difficult problem for counterfactual theories of causal responsibility. In this article, we explore a general framework for assigning responsibility in multiple agent contexts. We draw on the structura...

Rises in new HIV infections and the return of the hyper-epidemics of sexually transmissible infections have occurred among gay men in North America, Western Europe, Australia and New Zealand. If you look beneath the surface, discourses of failed responsibility and blame are a common reaction among gay men, educators, doctors and governments. When HIV first spread among gay communities in the la...

Received 7 September 2006 Revised 30 November 2006 Accepted 6 December 2006 Unhealthy lifestyle contributes significantly to the burden of disease. Scarce medical resources that could alternatively be spent on interventions to prevent or cure sufferings for which no one is to blame, are spent on prevention or treatment of (the risk of) disease that could be avoided through individual lifestyle ...

BACKGROUND Ocular alkali burns can be associated with a poor visual outcome. The release of collagenases and proteases after the injury leads to corneoscleral melting. The role of topical steroids in such patients is controversial as they have been postulated to exacerbate corneoscleral melting. METHODS 30 patients were reviewed retrospectively after admission to King's College Hospital with ...

Implementation often occupies a problematic position in accounts of strategy. It is often seen as a separate and low level activity. The assumption of separateness contradicts empirical evidence, while the assumption of low level activity portrays implementation as simple and automatic despite evidence that implementation often fails. We propose to resolve this difficulty by regarding implement...

OBJECTIVE To determine concentrations of ofloxacin and ciprofloxacin hydrochloride in aqueous humor after topical or combined topical and oral administration in eyes with filtering blebs. DESIGN A prospective, investigator-masked, randomized, controlled comparative study involving 36 eyes of 34 patients with functioning filtering blebs who were to undergo cataract surgery. Treatment groups re...