نتایج جستجو برای: topical immunotherapy
تعداد نتایج: 87287 فیلتر نتایج به سال:
introduction: infection is the most common complication of burn and one of the most important causes of mortality and morbidity in burned patients. topical antibiotics have important role in prevention and treatment of infection and reduction of mortality in burned patients. increases of use of antibiotics cause microbial resistance. methods: to determine microbial resistance to three topical a...
background medical sphincterotomy has gained popularity as a treatment for anal fissure. calcium channel blockers in topical forms could also be appropriate with low adverse effects. objectives this was a prospective randomized controlled trial to compare topical and oral nifedipine in the treatment of chronic anal fissure. patients and methods a prospective randomized controlled trial was cond...
With the recent approval by the FDA of an immunotherapy for prostate cancer and another positive immunotherapy trial in melanoma, immunotherapy may finally be coming of age. So what will it take for it to become part of the standard treatment for glioblastoma? To put this question into perspective, we summarize critical background information in neuro-immunology, address immunotherapy clinical ...
In the past two decades, immunotherapy has become a novel therapeutic modality for cancer patients. In this therapeutic modality, the immune system of patient’s body is augmented to acquire the ability of recognition and destruction of tumor/cancer cells. Cancer immunotherapy is divided into two forms: passive immunotherapy and active immunotherapy. In passive immunotherapy monoclonal antibodie...
Many investigators believe that immunotherapy will be the only selected treatment for leishmaniasis in the future. Leishmanization, vaccination or injection of stimulating mediators are among various forms of immunotherapy. In this pilot study, 5 volunteers with cutaneous leishmaniasis due to L.tropica were treated with 4 weekly intralesional injections of autologous buffy coat. Cytological and...
Tumor outcomes (progression, response to immunotherapies) are influenced by tumor-intrinsic and the tumor-immune microenvironment (TiME) factors. To overcome existing limitations of phenotyping tumors using single-time, single-siteex vivo biopsies in predicting tumor behavior, we propose an integrated dynamic approach for TiME combining inflammation, vasculature/ angiogenesis features through h...
BACKGROUND The published results regarding lymphocytes immunotherapy for unexplained recurrent miscarriage (uRM) patients are conflicting due to different screening criteria and therapeutic protocols. The objective of the present study is to evaluate the effectiveness of immunotherapy using low-dose lymphocytes in patients with uRM and Th1/Th2/Treg paradigm disorders. METHODS Sixty-four uRM p...
The house dust mite is a major cause of respiratory allergy worldwide. The management of mite allergy is based on avoidance measures, drug treatment, and allergen immunotherapy, but only allergen immunotherapy is able to modify the natural history of the disease. Injectable subcutaneous immunotherapy was introduced a century ago, while sublingual immunotherapy was proposed in the 1980s and emer...
Killer-cell immunoglobulin-like receptors (KIRs) are a family of glycoproteins expressed primarily on natural killer cells that can regulate their function. Inhibitory KIRs recognize MHC class I molecules (KIR-ligands) as ligands. We have reported associations of KIRs and KIR-ligands for patients in two monoclonal antibody (mAb)-based trials: (1) A Children's Oncology Group (COG) trial for chil...
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