In three experiments, chloroform was administered to mice by gavage in a toothpaste base or in arachis oil, in doses up to 60 mg/kg/d on 6 days/wk for 8 wks. Control groups were left untreated or given vehicle only. In general, there were more survivors in chloroform-treated groups than in the controls. In the case of the males of three strains (C57BL, CBA and CF/1), treatment was associated wi...

The purpose of this study was to evaluate the effect of the application of fluoride products on the development of enamel caries in deciduous teeth. A total of 108 deciduous teeth were chosen for the study. Acid-resistant varnish was applied on the teeth, leaving only one area of 5 mm x 1 mm of dental enamel exposed. The teeth were allocated randomly to one of the following groups: 1) control -...

Dental caries is the most common oral health issue for general population. not only affects quality of life but also brings economic burden to individual and society. The aim this study was determine prevalence dental associated factors among patients. An analytical, cross-sectional conducted patients visiting Department Oral Medicine Nepal Medical College Hospital Kathmandu. results showed tha...

As there is no homeostatic mechanism for maintaining circulating fluoride (F) in the human body, the concentration may decrease and increase again when intake is interrupted and re-started. The present study prospectively evaluated this process in children exposed to F intake from water and toothpaste, using F in urine as a biomarker. Eleven children from Ibiá, Brazil (with sub-optimally fluori...

OBJECTIVE Toothbrush abrasion is significant in the development of tooth wear, particularly when combined with erosion. This in vitro study aimed to evaluate the impact of toothpaste slurry abrasivity and toothbrush filament stiffness on abrasion of eroded enamel. MATERIAL AND METHODS Eroded enamel samples (hydrochloric acid, pH: 2.6, 15 s) were brushed with 40 strokes in an automatic brushin...

OBJECTIVE To obtain information on the level of total fluoride intake from food, beverages and toothpaste by children at the age of 22-25 months of low and high socioeconomic status (SES) in major Colombian cities. METHODS Daily fluoride intake was assessed by the duplicate plate method and by recovered toothpaste solution during a 3-day period and afterwards analysed by the microdiffusion me...

OBJECTIVE High and low concentration NaF regimes have shown caries protective properties, but the preventive effect against erosive/abrasive wear is unclear. AIM. To measure the inhibiting effect on enamel wear of low and highly concentrated sodium fluoride (NaF) toothpastes and a stannous (SnF2) fluoride gel in a single-blind, randomized in situ study, using a White Light Interferometer. MAT...

INTRODUCTION Different systems of traditional medicine of the Indian subcontinent, have used Acacia chundra Willd, Adhatoda vasica Nees., Mimusops elengi L., Piper nigrum L., Pongamia pinnata L. Pirerre, Quercus infectoria Olivier., Syzygium aromaticum L., Terminalia chebula Retz., Zingiber officinale Roscoe., individually or in combinations, to cure oral diseases. OBJECTIVE To investigate th...

Purpose: To evaluate the effects of herbal-based toothpastes with different contents on viability L929 cells.Methods: Herbal-based {Aloe vera - propolis herbal toothpaste, Group 1; Parodontax, 2; Toothpaste miswak, and tea tree extract, 3, Dent natural protective toothpaste clay, 4; Gano fresh, 5} were diluted (1:1, 1:2, 1:4, 1:8, 1:16, 1:32) in Dulbecco’s modified Eagle’s medium. fibroblast ce...