OBJECTIVE To correlate the type of dental occlusion and the type of pharyngeal lymphoid tissue obstruction in children. DESIGN Cross-sectional study. SETTING Ambulatory ear, nose, and throat clinic of Faculdade de Medicina da Universidade de São Paulo. PATIENTS One hundred fourteen children aged 3 to 12 years presenting with mouth breathing and snoring due to tonsil and/or adenoid enlarge...

OBJECTIVE To identify physical findings that can be standardized to predict the presence and the severity of obstructive sleep apnea (OSA). STUDY DESIGN One hundred seventy-two patients who answered questionnaires with responses that suggested they might have OSA were included in this prospective study. METHODS All patients underwent a physical examination and polysomnography. The physical ...

Systemic lupus erythematosus (SLE) is a generalized autoimmune disease characterized by abnormal B cell activation and the occurrence of increased frequencies of circulating plasma cells (PC). The molecular characteristics and nature of circulating PC and B cells in SLE have not been completely characterized. Microarray analysis of gene expression was used to characterize circulating PC in subj...

The data about the topography and morphology of the paraepiglottic tonsil (tonsilla paraepiglottica; TPE) in pigs are not enough. The purpose of the present investigation was to determine its topography, morphological traits and some morphometric parameters in Bulgarian White × Landrace pig crosses. It was found that TPE was situated in pars laryngea pharyngis, dorsolaterally to vallecula epigl...

OBJECTIVES Although human papillomavirus (HPV) infection is considered as a favorable prognostic factor in oropharyngeal cancer, the prognosis of HPV-associated tonsil cancer has rarely been studied especially when surgery was the main treatment. In this study, the authors investigated the effect of p16 over-expression (HPV infection) on tonsil cancer prognosis according to the type of treatmen...

Human T cell development within the thymus is a well-characterized event, and it is known that a functional thymus is required for normal T cell generation to take place. Individuals with poor thymic function, from either congenital abnormality or post-natal injury, have a difficult time mounting a proper immune response and suffer from debilitating immune deficiency. Thus, it would be highly b...

Patients with infectious mononucleosis (IM) undergoing primary EBV infection show large expansions of EBV-specific CD8+ T cells in the blood. While latent infection of the B cell pool is quickly controlled, virus shedding from lytically infected cells in the oropharynx remains high for several months. We therefore studied how responses localize to the tonsil, a major target site for EBV, during...

Preclinical diagnostic tests for transmissible spongiform encephalopathies have been described for mule deer (Odocoileus hemionus), using biopsy tissues of palatine tonsil, and for sheep, using lymphoid tissues from palatine tonsil, third eyelid, and rectal mucosa. The utility of examining the rectal mucosal lymphoid tissues to detect chronic wasting disease (CWD) was investigated in Rocky Moun...