BACKGROUND Ability to predict the efficacy of treatment in Alzheimer disease (AD) may be very useful in clinical practice. Cognitive predictors should be investigated alongside with the demographic, genetic, and other predictors of treatment efficacy. The aim of this study was to establish whether the baseline measures of CANTAB tests and their changes due to the first donepezil dose are able t...

In article number 2004560, Kolleboyina Jayaramulu, Deepak Dubal, Radek Zboril, Roland A. Fischer, and co-workers report covalent attachment of graphene acid (GA) an amine-functionalized metal–organic framework (UiO-66-NH2) via the amide bond. The hybrid GA@UiO-66-NH2 acts as effective charge-storing material with a remarkable capacitance. They construct asymmetric supercapacitor (ASC) using pos...

Magnetic molecular imprinted polymers nanozyme MIPs@Fe3O4-NH2 with high specificity and excellent peroxidase-like activity was prepared for colorimetric detection of protocatechuic acid (PCA). Firstly, obtained by self-polymerization dopamine as a functional monomer on the surface Fe3O4-NH2, enabling formation specific recognition cavities. Later, elution PCA using polar solvents resulted in cr...

Hydrogen sulfide (H2S) is an industrial exhausted gas that highly toxic to humans and the environment. Combining desulfurization fabrication of cathode materials for lithium–sulfur batteries (LSBs) can solve this issue with a double benefit. Herein, amino-functionalized lotus root-like carbon nanofibers (NH2-PLCNFs) are prepared by amination electrospinning under dielectric barrier discharge pl...

As a potential negative electrode material for lithium-ion batteries (LIBs), silicon has relatively high specific lithium storage capacity. However, the large volume change during cycle may result in isolation with current collector and therefore rapid capacity decay cycling. The poor electric conductivity of limits high-power density application LIBs. To meet above challenges, stable Si/Ti3C2T...

We expressed the NH2-terminal domain of the multidomain, multifunctional enzyme, 10-formyltetrahydrofolate dehydrogenase (FDH), using a baculovirus expression system in insect cells. Expression of the 203-amino acid NH2-terminal domain (residues 1-203), which is 24-30% identical to a group of glycinamide ribonucleotide transformylases (EC 2.1.2.2), resulted in the appearance of insoluble recomb...

Expression of chimeras, composed of portions of two different glucose transporter isoforms (GLUT-1 and GLUT-4), in CHO cells had indicated that the cytoplasmic NH2 terminus of GLUT-4 contains important targeting information that mediates intracellular sequestration of this isoform (Piper, R. C., C. Tai, J. W. Slot, C. S. Hahn, C. M. Rice, H. Huang, D. E. James. 1992. J. Cell Biol. 117:729-743)....

Recording simultaneously in vitro the changes of endoluminal pressure (index of circular muscle activity) and isometric tension (index of longitudinal muscle activity), we examined the mechanisms responsible for the apamin-sensitive relaxant and contractile responses induced by protease-activated receptor (PAR)-1 and PAR-2 activating peptides, SFLLRN-NH2 and SLIGRL-NH2, respectively, in rat col...