The cytotoxicity and genotoxicity of the stilbenes (E)-methyl-4-(3-5-dimethoxystyryl)benzoate (ester), (E)-4-(3-5-dimethoxystyryl)aniline (amino), (Z)-1,3-dimethoxy-5-(4-methoxystyryl)benzene (cis-TMS) and (E)-1,3-dimethoxy-5-(4-methoxystyryl)benzene (trans-TMS) were investigated in this work. Structural modifications of resveratrol, a naturally occurring stilbene, have been previously performe...

There is consensus that the left hemisphere plays a dominant role in language processing, but functional imaging studies have shown that the right as well as the left posterior inferior frontal gyri (pIFG) are activated when healthy right-handed individuals make phonological word decisions. Here we used online transcranial magnetic stimulation (TMS) to examine the functional relevance of the ri...

UNLABELLED Transcranial magnetic stimulation (TMS) is a promising method for both investigation and therapeutic treatment of psychiatric and neurologic disorders and, more recently, for brain mapping. This study describes the application of navigated TMS for motor cortex mapping in patients with a brain tumor located close to the precentral gyrus. MATERIALS AND METHODS In this prospective stu...

Background: Glioma stem cells (GSCs) are a critical therapeutic target of glioblastoma multiforme (GBM). Methods: The effects of a G-quadruplex ligand, telomestatin (TMS), were evaluated using patient-derived GSCs, non-stem tumor cells (non-GSCs), and normal fetal neural precursors in vitro and in vivo. The molecular targets of TMS were determined by immunofluorescence in situ hybridization (iF...

In this work, a surface current plasma model is coupled to volume integral formulation for studying the interaction between tokamak tearing modes (TMs) and machine metallic structures surrounding plasma. By evaluating passive response on set of pickup probes, TMs' amplitude estimated.

Abstract Coupling transcranial magnetic stimulation with electroencephalography (TMS-EEG) allows recording the EEG response to a direct, non-invasive cortical perturbation. However, obtaining genuine TMS-evoked potentials (TEPs) requires controlling for several confounds, including auditory evoked (AEPs) associated TMS discharge noise (TMS click). To rule out AEPs from TEPs, AEP can be mathemat...

Delivering transcranial magnetic stimulation (TMS) shortly after the end of a visual stimulus can cause a TMS-induced 'replay' or 'visual echo' of the visual percept. In the current study, we find an entrainment effect that after repeated elicitations of TMS-induced replay with the same visual stimulus, the replay can be induced by TMS alone, without the need for the physical visual stimulus. I...

Transcranial magnetic stimulation (TMS) is an increasingly common technique used to selectively modify neural processing. However, application of TMS is limited by uncertainty concerning its physiological effects. We applied TMS to the cat visual cortex and evaluated the neural and hemodynamic consequences. Short TMS pulse trains elicited initial activation (approximately 1 minute) and prolonge...

Recent years have seen increasing numbers of transcranial magnetic stimulation (TMS) studies focusing on somatosensory processing. Most have centered on the primary somatosensory functions of tactile detection, localization and discrimination, and have applied TMS to primary somatosensory areas. These studies confirm the basic functions of primary somatosensory areas, and the behavioural and ph...

Transcranial magnetic stimulation (TMS) applied over the primary motor cortex (M1), elicits motor-evoked potentials (MEPs) in contralateral limb muscles which are valuable indicators of corticospinal excitability (CSE) at the time of stimulation. So far, most studies have used single-coil TMS over one M1, yielding MEPs in muscles of a single limb-usually the hand. However, tracking CSE in the t...