In this study, multiphoton excitation was utilized to image normal and carious dental tissues noninvasively. Unique structures in dental tissues were identified using the available multimodality (second harmonic, autofluorescence, and fluorescence lifetime analysis) without labeling. The collagen in dentin exhibits a strong second harmonic response. Both dentin and enamel emit strong autofluore...

Molecules that have no center of symmetry are able to convert light to its second harmonic, at twice the frequency and half the wavelength. This only happens with any efficiency at very high light intensities such as are given by a pulsed laser, and because the efficiency of the process depends on the square of the intensity, it will be focal plane selective in exactly the same way as two-photo...

cardiac magnetic resonance imaging (cmri) is a well-established noninvasive imaging modality in clinical cardiology. its ability to provide tissue characterization make it well suited for the study of patients with cardiac diseases. we describe a multi-modality imaging evaluation of a 45-year-old man who experienced a near drowning event during swimming. we underline the unique capability of ti...

The technique of Harmonic Motion Imaging (HMI) utilizes the localized stimulus of the oscillatory ultrasonic radiation force as produced by two overlapping beams of distinct frequencies, and estimates the resulting harmonic displacement in the tissue in order to assess its underlying mechanical properties. In this paper, we studied the relationship between the measured displacement and the gel/...

background : near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. this is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue. method : in this paper the different medical applications, various imaging and simulation techniques of nirs imaging is describe...

Progressive force loss in Duchenne muscular dystrophy is characterized by degeneration/regeneration cycles and fibrosis. Disease progression may involve structural remodeling of muscle tissue. An effect on molecular motorprotein function may also be possible. We used second harmonic generation imaging to reveal vastly altered subcellular sarcomere microarchitecture in intact single dystrophic m...