Styloid process of temporal bone is a slender projection attached to base of the skull and extends downwards, forwards and slightly medially. From its extremity the stylohyoid ligament passes downwards and forwards to the lesser horns of hyoid bone. The process is covered laterally by the parotid gland, facial nerve crosses its base and the external carotid artery crosses its tip, as they lie w...

Objective was to introduce a modified appliance and treatment protocol for presurgical nasoalveolar molding in a new born baby presenting with unilateral cleft of the lip and palate. This treatment comprises use of an orthopedic plate with acrylic nasal stent, in combination with adhesive steri-strip. The plate is adjusted every week for alveolar molding. For nasal molding, soft acrylic is adde...

kar9 was originally identified as a bilateral karyogamy mutant, in which the two zygotic nuclei remained widely separated and the cytoplasmic microtubules were misoriented (Kurihara, L.J., C.T. Beh, M. Latterich, R. Schekman, and M.D. Rose. 1994. J. Cell Biol. 126:911-923.). We now report a general defect in nuclear migration and microtubule orientation in kar9 mutants. KAR9 encodes a novel 74-...

PURPOSE The purpose of this study was to compare the characteristics of shaped microcatheters, including shapability, durability, and luminal changes. MATERIALS AND METHODS Eleven brands of steam-shaped microcatheters and one brand of preshaped microcatheter were evaluated. There were 2 nonreinforced and 10 reinforced devices supported by coils. For evaluation of shapability, the tip angle of...

Upon exposure to mating pheromone, Saccharomyces cerevisiae undergoes cellular differentiation to form a morphologically distinct cell called a "shmoo". Double staining experiments revealed that both the SPA2 protein and actin localize to the shmoo tip which is the site of polarized cell growth. Actin concentrates as spots throughout the shmoo projection, while SPA2 localizes as a sharp patch a...

Recently, in Korea, the septal extension graft from the septum or rib has become a common method of correcting a small or short nose. The success rate of this method has led to the blind faith that it provides superior tip projection and definition, and to the failure to notice its weaknesses. Even if there is a sufficient amount of cartilage, improper separation or fixation might waste the car...

BACKGROUND Various methods for primary repair of bilateral cleft lip have been developed, but they often produce inadequate results, such as an upturned nose or a short columella. We perform primary lip repair with muscle reconstruction to correct depression of the nasal floor and inferoposterior displacement of the alar base. Then, open rhinoplasty to project the nasal tip is performed during ...

OBJECTIVE To present technical modifications to the original presurgical nasal remodeling appliance introduced in 1991. The purpose of the modifications is to improve the cleft nasal deformity before unilateral and bilateral cleft lip repair. METHOD The principle behind this technique, known as dynamic presurgical nasal remodeling (DPNR), is the use of the force generated during suction and s...

We report a highly efficient, simple, and non-infective method for labeling individual long-range projection neurons (LRPNs) in a specific location with enough sparseness and intensity to allow complete and unambiguous reconstructions of their entire axonal tree. The method is based on the "in vivo" transfection of a large RNA construct that drives the massive expression of green fluorescent pr...

When yeast cells sense mating pheromone, they undergo a characteristic response involving changes in transcription, cell cycle arrest in early G1, and polarization along the pheromone gradient. Cells in G2/M respond to pheromone at the transcriptional level but do not polarize or mate until G1. Fus2p, a key regulator of cell fusion, localizes to the tip of the mating projection during pheromone...