Approximately one-quarter of ischemic strokes involve the vertebrobasilar arterial system that includes the upstream flow confluence and downstream flow divergence. A patient-specific hemodynamic analysis is needed to understand the posterior circulation. The objective of this study is to determine the distribution of hemodynamic parameters in the vertebrobasilar system, based on computer tomog...

This article presents a data-driven model based on modal decomposition, applied to approximate the low-order statistics of spatially averaged wall-shear stress in turbulent channel flow over porous wall with two anisotropic permeabilities, producing drag increase or reduction when compared case an isotropic wall. The is comparable neural network architecture using linear map classification. To ...

Single-phase turbulent pipe flows are analysed utilizing a new theory presented in parallel paper. Arguably this implies improvements matching modelling results with experimental observations: To illustrate, unique for these computations is that 1st law balance agreement between simulations and corresponding experiments achieved, while resolving the time-averaged fluid flow velocity (including ...

Flows around an axisymmetric body of revolution at a zero yaw angle were studied using hybrid Reynolds-averaged Navier–Stokes (RANS)/large eddy simulation (LES) approach, which employed full Reynolds stress model (RSM) in the RANS branch with aim accounting for anisotropy, streamline curvature, and flow separations boundary layer. The SUBOFF without appendages was applied to conduct simulations...

Received Mar 10, 2016 Revised May 12, 2016 Accepted May 24, 2016 This study focuses on the behavior of blood flow through diseased artery in the presence of porous effects. The laminar, incompressible, fully developed, non-Newtonian in an artery having axially non-symmetric but radially symmetric stenosis is numerically studied. Here blood is represented as Herschel-Bulkley fluid model and flow...

Kawasaki Disease (KD) is the leading cause of acquired pediatric heart disease. A subset of KD patients develops aneurysms in the coronary arteries, leading to increased risk of thrombosis and myocardial infarction. Currently, there are limited clinical data to guide the management of these patients, and the hemodynamic effects of these aneurysms are unknown. We applied patient-specific modelin...

Objectives This study aims at comparing by means of computational fluid-dynamics (CFD) the hemodynamics before and after carotid endarterectomy (CEA), and, after CEA, between patch graft (PG) and direct suture (DS) closures. Design We analyzed wall shear stress (WSS), velocities, and vorticity before and after CEA, to highlight the effect of surgery on hemodynamics, and time averaged WSS (TAWSS...

The efficacy of large-eddy simulation ~LES! with wall modeling for complex turbulent flows is assessed by considering turbulent boundary-layer flows past an asymmetric trailing-edge. Wall models based on turbulent boundary-layer equations and their simpler variants are employed to compute the instantaneous wall shear stress, which is used as approximate boundary conditions for the LES. It is de...

BACKGROUND Intimal hyperplastic thickening (IHT) is a frequent cause of prosthetic bypass graft failure. Induction and progression of IHT is thought to involve a number of mechanisms related to variation in the flow field, injury and the prosthetic nature of the conduit. This study was designed to examine the relative contribution of wall shear stress and injury to the induction of IHT at defin...

The deformation of red blood cells in microvessels was investigated numerically for various vessel diameters, hematocrits, and shear rates. We simulated blood flow in circular channels with diameters ranging from 9 to 50 μm, hematocrits from 20% to 45%, and shear rates from 20 to 150 s(-1) using a particle-based model with parallel computing. The apparent viscosity predicted by the simulation w...