Present work aims at multi-mechanical surface treatment of Ti-6Al-4V based-miniplate implant manufactured by electrical discharge machining (EDM) for biomedical use. Mechanical surface treatment consists of consequent use of ultrasonic cleaning, rotary tumbler polishing, and brushing. Surface layers are analyzed employing scanning electron microscopy and energy dispersive X-ray spectroscopy. Al...

The objective of this work was to demonstrate the effect of fluoride and propolis extract on the corrosion behavior of commercially pur titanium (cp-Ti grade 2) in artificial saliva. The inhibition studies were approved out on cp-Ti as dental implant in Fusayama-Meyer with the propolis extract using potentiodynamic polarization and Electrochemical Impedance Spectroscopy (EIS). Parameters, such ...

Three different implants, bare Ti-6Al-4V alloy, Ti-6Al-4V alloy coated with plasma-sprayed hydroxyapatite (PSHA), and Ti-6Al-4V alloy coated with electrochemically deposited hydroxyapatite (EDHA), were implanted into canine trabecular bone for 6 h, 7, and 14 days, respectively. Environmental scanning electron microscopy study showed that PSHA coatings had higher bone apposition ratios than thos...

This review covers several basic methodologies of surface treatment and their effects on titanium (Ti) implants. The importance of each treatment and its effects will be discussed in detail in order to compare their effectiveness in promoting osseointegration. Published literature for the last 18 years was selected with the use of keywords like titanium dental implant, surface roughness, coatin...

Dental implants have been widely used for the replacement of missing teeth in the clinic, but further improvements are needed to meet the clinical demands for faster and tighter osseointegration. In this study, we fabricated safe and biocompatible chitosan (CS)/hyaluronic acid (HA) nanoparticles to deliver microRNA-21 (miR-21) and thereby accelerate osteogenesis in human bone marrow mesenchymal...

Appropriate surface chemistry between a material and its surrounding biological environment is crucial to the eventual integration and performance of any implant, whether metal, plastic, or ceramic. A robust peptide-based coating technology capable of easily modifying the surface of titanium (Ti) metal through noncovalent binding is described. A short peptide possessing affinity for Ti was iden...

Introduction While contemporary prosthetic devices provide some restoration of function to individuals who have lost a limb, there are ongoing efforts to develop bio-integrated prostheses that would enhance functionality by providing motor control and sensory feedback. A critical step in the development of a bio-integrated prosthesis will be establishing longterm, secure fixation to the remnant...

Prolonged inflammation induced by orthopedic metallic implants can critically affect the success rates, which even lead to aseptic loosening and consequent implant failure. In case of adverse clinical conditions involving osteoporosis, trauma corrosion-wear in peri-implant region, reactive oxygen species (ROS) activity is enhanced leads increased oxidative stress. Metallic materials (such as ti...

Enhancing vitamin D-induced human osteoblast (hOB) maturation at bone biomaterial surfaces is likely to improve prosthesis integration with resultant reductions in the need for revision arthroplasty consequent to aseptic loosening. Biomaterials that are less appealing to microorganisms implicated in implant failures through infection are also highly desirable. However, finding surfaces that enh...

INTRODUCTION Earlier studies show that a Cochlear Implant (CI), capable of providing intracochlear electrical stimulation independent of environmental sounds, appears to suppress tinnitus at least for minutes. The current main objective is to compare the long-term suppressive effects of looped (i.e. repeated) electrical stimulation (without environmental sound perception) with the standard stim...