Subcellular fractionation of bovine thyroid tissue by differential pelleting and isopycnic gradient centrifugation in a zonal rotor indicated that NAD(+) glycohydrolase is predominantly located and rather uniformly distributed in the plasma membrane. Comparison of NAD(+) glycohydrolase activities of intact thyroid tissue slices, functional rat thyroid cells in culture (FRT(l)) and their respect...

the common midline neck masses include thyroglossal duct cyst, lipomas, thyroid tumor or cyst and rarely a midline lymph node, particularly the node just above the thyroid isthmus. thyroid tuberculosis (ttb) is a rare cause of thyroid disease and therefore only occasionally included in the differential diagnosis. in this study we tried to explain the clinical and paraclinical manifestations of ...

Previously, a number of workers have described preparations of thyroid tissue which catalyze the iodination of free or proteinbound tyrosine (l-7). It was demonstrated that the enzymatic activity was mitochondrial in location, and depending upon the method of preparation or assay, various metals and cofactors were implicated in the reaction. Serif and Kirkwood (1, 2) found that addition of cert...

UNLABELLED BACKGROUND Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression and prophylaxis of bipolar disorders. Thyroid abnormalities associated with treatment with lithium have been widely reported in medical literature to date. These include goitre, hypothyroidism, hyperthyroidism and autoimmune thyroiditis. This current review explores the va...

Radioiodine activity required for remnant thyroid ablation is of great concern, to avoid unnecessary exposure to radiation and minimize adverse effects. We investigated clinical outcomes of remnant thyroid ablation with a low radioiodine activity in Korean patients with low to intermediate-risk thyroid cancer. For remnant thyroid ablation, 176 patients received radioiodine of 1.1 GBq, under a s...

Over the past few years increasing evidence has suggested the nongenomic effects of thyroid hormone, such as the activation of the signal transduction pathways and the activation of nuclear factor-kappaB by the induction of oxidative stress. The present study was undertaken to investigate the effect of thyroid hormone on human polymorphonuclear leukocytes (PMNLs) which are known as important so...

Background: Based on the results of a histological study of removed TG tissue NGAIT was found in 10, 4% of the patients (1, 2). At the same time, there are processes of both thyroid epithelium metaplasia and lymphoid tissue hyperplasia that, undoubtedly, can be considered as an optional precancerous condition (3-8). The option when cytomorphological and immunocytochemical examinations are carri...

Ghrelin is an orexigenic peptide synthesized mainly by stomach and hypothalamus. Ghrelin decreases secretion of thyroid hormones. Testosterone is an esteroidogenic hormone that exerts stimulatory effects on Hypothalamus-Pituitary-Thyroid (HPT) axis activity. The aim of the present study was to investigate the effect of interactions between the central injection of ghrelin and testosterone on me...

background: there are inter-observer disagreements between papillary thyroid carcinoma (ptc) with other follicular lesions of thyroid in aspect of diagnosis. cd56 is present on follicular epithelial cells of the normal thyroid. we evaluated the diagnostic value of cd56 expression in ptc, follicular thyroid lesions, and follicular thyroid neoplasms. materials and methods: seventythree cases diag...

Thyroid function decreases and cold exposure response becomes impaired with increasing age. We investigated the age-related changes in thyroid structure and function and cold-induced changes in the thyroid activity of aging rats. Thirty-two male Sprague-Dawley rats were randomly divided into four groups (8 rats per group): young (7 months) and old (22 months) groups exposed to room temperature ...