the role of microbiota in health and disease is the subject of rigorous investigation. several studies have demonstrated that microbiota and the pattern-recognition receptors contribute to intestinal tumourigenesis; the exact mechanism of which is still obscure. myd88 is the downstream effector of all toll-like receptors (tlrs) except tlr3. however, the alternative myd88-independent pathway is ...

just regarding different risk factors for antibiotic resistant uropathogenes, it seems justice to improve diagnostic power for drug resistant uropathogenes and well appropriate empirical therapy. 300 and 145 cases of clinicopathologically diagnosed nosocomial and spinal cord injured (sci) associated urinary tract infection (uti), respectively, were considered as our samples included in our 24 m...

urinary tract infection (uti) is a neonatal life threatening infection which is usually treated with ampicillin plus an aminoglycoside or a third-generation cephalosporin. recently, growing number of escherchia coli species resistant to ampicillin and aminoglycosides have raised concerns regarding the necessity to change the empirical therapy. this motivates us to determine neonatal uti clinica...

results amc-susceptible esbl-producing escherichia coli, klebsiella pneumoniae and k. oxytoca were identified as the causative agents in 31, 14, and 1 patients, respectively. thirty-nine (84.7%) out of 46 patients were successfully treated with oral amc. additionally, 2 (4.3%) patients’ urine cultures turned to be negative, though their clinical complaints and leukocyturia had continued. in the...

conclusions the trat gene and pai markers were highly prevalent among upec strains isolated from patients in kashan, iran; therefore these determinants could be used as targets for prophylactic interventions. also there was a high level of resistance against the antibiotics commonly used for urinary tract infection treatment. to reach better therapeutic outcomes, treatment regimens have to be m...

conclusions: the most common infectious episode among spinal cord injury patients was found to be urinary tract ınfection. e. coli was the most common microorganism isolated from urine samples. antibiotic use in the previous 2 weeks or 3 months, hospitalization during the last one-year and previous diagnosis of urinary tract ınfection were the risk factors identified for the development of infe...

background and objective:  early diagnosis of streptococcus agalactiae remains difficult, since symptoms are very nonspecific. its frequency has not been completely investigated in urinary tract pathogen of pregnant ant and non pregnant women in iran. the aim of this study was determining the frequency of group b streptococci in female patients. materials and methods: a total of 11800 urine sp...

background and purpose: posterior urethral valve (puv) is one of the most severe urinary tract anomalies presenting as antenatal hydronephrosis that could lead to severe dilatation and functional impairment of one or both kidneys. the aim of this study was to analyze our experience on patients with a diagnosis of puv. materials and methods: in this prospective study neonates with a diagnosis of...

objectives we assessed the prevalence of three common viruses including; respiratory syncytial virus (rsv), human rhinovirus (hrv), and human metapneumovirus (hmpv), in children with acute wheezing. patients and methods ninety six wheezy children, 48 males (50%) and 48 females (50%)under the age of 5 years, were enrolled in the study. all patients visited as outpatients or inpatients when refer...

this study shows that ichonology can be used to refine sequence stratigraphy as well as to interpret the depositional environment of the kalat formation (upper maastrichtian) in the central kopeh- dagh basin (ne iran), dareh-gaz section. field studies and petrography of these deposits led to recognize four lithofacies and nine subfacies that formed in the tidal flat (lithofacies a), lagoon (lit...