نتایج جستجو برای: thymidine kinase
تعداد نتایج: 236828 فیلتر نتایج به سال:
The uptake of thymidine into an acid-soluble pool in normal hamster embryo cells and hamster tumor cells transformed by polyoma virus was studied. It was found that tumor cells exhibited a 4-fold higher capacity than normal cells to incorporate thymidine as phosphorylated products into this pool. This was correlated with a 5to 10-fold higher activity of thymidine kinase in the tumor cell lines....
We evaluated positron emission tomographic imaging of pulmonary transgene expression, using an enhanced mutant herpes simplex virus-1 thymidine kinase as the reporter gene, in the lungs of normal rats. Sixteen rats were studied 3 days after an intratracheal administration of 5 x 10(9) to 1 x 10(11) viral particles of a replication-incompetent adenovirus containing a fusion gene of the mutant ki...
The activities of thymidine kinase (TK) isoenzyme 1 and 2 were examined in extracts of human benign or malignant lymphoid tissue and correlated with degrees of morphological differentiation. TK2 activity occurred in peripheral blood lymphocytes of normal individuals, patients with chronic lymphocytic leukemia, or solid lymphoid tissue, exhibiting either nonneoplastic histological findings or th...
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