materials and methods in the present study, a potent nk-producing strain was isolated from cow milk and identified. to enhance the yield of nk, effect of various parameters such as ph, temperature, carbon source, nitrogen source and inoculum size were optimized. strain improvement of p. aeruginosa cmss was done by random uv-mutagenesis. nattokinase was partially purified and the activity was de...

Management of prosthetic valve thrombosis in pregnancy Tratamento da trombose da válvula protética na gravidez Dear Editor, We read with great interest the article by Cardoso et al. which was recently published in the Journal. 1 We thank the authors for the contribution of their report describing thrombolytic therapy (TT) with streptokinase (SK) in a pregnant patient with prosthetic valve throm...

OBJECTIVE Deep venous thrombosis is a major health problem. Thrombolytic therapies are effective in recanalizing the veins and preventing post-thrombotic complications, but there is no consensus on selection criteria. The aim of this study was to investigate a fibrin-specific MRI contrast agent (EP-2104R) for the accurate quantification of thrombus' fibrin content in vivo and for the identifica...

I t has been recognized for over a century that stasis of blood, abnormalities of the vessel wall, and changes in the soluble and formed elements of the blood are the major contributors to thrombosis. For venous thrombosis, stasis and local alterations in blood elements are most important, since major pathologic changes are not routinely seen in the vessel wall at the nidus of a venous thrombus...

BACKGROUND The efficacy of fibrinolytic therapy is limited by the small surface area of the clot that is available for the binding of the thrombolytic agent, such as tissue-type plasminogen activator (t-PA). We hypothesized that exposure of the clot to ultrasound during thrombolytic treatment could enhance lysis through perturbation of the thrombus, which would expose additional fibrin binding ...

Abstract Coronary artery aneurysm is a rare disorder with prevalence in male population. The most commonly involved vessel the right coronary followed by anterior descending artery. frequent etiologies are atherosclerosis and Kawasaki disease. treatment of aneurysms significant stenosis often surgical, implantation covered stents case saccular aneurysms. In without stenosis, medical therapy sui...

background : treatment delay in the management of st-elevation myocardial infarction conversely correlates with prognosis and survival of the patients. this study aimed to investigate factors associated with delay in the thrombolytic therapy of these patients in tehran. methods : between 2007 and 2010, the interval between the self-reported time of the onset of symptoms and initiation of the th...

INTRODUCTION AND OBJECTIVES Despite the rapid global uptake of transcatheter aortic valve implantation, valve trombosis has yet to be systematically evaluated in this field. The aim of this study was to determine the clinical characteristics, diagnostic criteria, and treatment outcomes of patients diagnosed with valve thrombosis following transcatheter aortic valve implantation through a system...