نتایج جستجو برای: threonine

تعداد نتایج: 19213  

1982
YUJI ODA YOSHIHISA NAKANO SHOZABURO KITAOKA

Two threonine dehydratases, I and 11, were found to occur in Euglena gracilis and each enzyme was purified partially. Like the biosynthetic threonine dehydratases of other organisms, dehydratase I was feedback-inhibited by isoleucine and not affected by adenylates. Dehydratase I1 was not influenced by branched-chain amino acids and adenylates. Occurrence of dehydratase 11, with a much higher ac...

Journal: :Biochemistry 2004
Richard S Mursinna Keun Woo Lee James M Briggs Susan A Martinis

A highly conserved threonine residue marks the amino acid binding pocket within the editing active site of leucyl-tRNA synthetases (LeuRSs). It is essential to substrate specificity for the Escherichia coli enzyme in that it blocks the cognate leucine amino acid from binding in the hydrolytic editing active site. We combined mutagenesis and computational approaches to elucidate the molecular ro...

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