Non-regular two-level fractional factorial designs, such as Plackett–Burman designs, are becoming popular choices in many areas of scientific investigation due to their run size economy and flexibility. The run size of nonregular two-level factorial designs is a multiple of 4. They fill the gaps left by the regular twolevel fractional factorial designs whose run size is always a power of 2 (4, ...

The challenge in developing oral drug delivery systems of poorly soluble basic drugs is primarily due to their pH dependent solubility. Cinnarizine (CNZ), a model for a poorly soluble basic drug, has pH dependent solubility; where it dissolves readily at low pH in the stomach and exhibits a very low solubility at pH values greater than 4. It is also characterized by a short half life of 3-6h, w...

In order to investigate the effect of Cd and Zn on uptake, concentration and the translocation factor of the Cd and Zn in the rice plant, a factorial experiment was conducted with four factors including two rice cultivars of Vandana and Hashemi, two waterlogged and non-waterlogged conditions and three levels of Zn and Cd (0, 5 and 10 mg kg-1 soil). The experiment was carried out in a randomized...

OBJECTIVES (1) To examine the psychometric properties of the Basic Empathy Scale (BES) with Spanish adolescents, comparing a two and a three-dimensional structure;(2) To analyse the relationship between the three-dimensional empathy and social and normative adjustment in school. DESIGN Transversal and ex post facto retrospective study. Confirmatory factorial analysis, multifactorial invarianc...