In 1811, Courtois noted a violet vapor arising from burning seaweed ash and Gay-Lussac subsequently identified the vapor as iodine, a new element. The Swiss physician Coindet, in 1813, hypothesized the traditional treatment of goiter with seaweed was effective because of its iodine content and successfully treated goitrous patients with iodine. Two decades later, the French chemist Boussingault...

At the time after the Second World War, endemic goiter was present in most parts of Croatia with a prevalence of more than 50% and presence of cretinism. In the village of Rude near Zagreb, goiter was detected in 85% of school children with 2.3% of cretins in the village population. In 1953 the first regulation on obligatory salt iodination, requiring 10 mg of potassium iodide (KI) per kg of sa...

Aim: To determine the outcome of thyroid surgery for treatment of multinodular goiter and compare subtotal and total thyroidectomy surgeries. Methods: This study was conducted at the department of Ear, Nose, Throat, Head and Neck Surgery, Hayat Medical Complex Peshawar from Jan. 2012 to June. 2012 (6months). This study included 60 patients with multinodular goiter. These patients were divided i...

The Hospital de Clínicas organized a free program of goiter detection by palpation. This campaign was aimed at the population of the metropolitan area of Greater Buenos Aires (11 million inhabitants), with the prerequisite that each participant should be quite unaware whether he/she was a carrier of any thyroid disease. Attendees were split into two groups, i.e., Random and Induced. The former ...

BACKGROUND Iodine deficiency has been identified as a significant public health problem in Iran. The main strategy for controlling iodine deficiency was nationwide salt iodination. Over 10 years after starting this program, goiter is still endemic in school children. Iron deficiency may have interfered with the iodine intervention program. The objective of the present study was to evaluate the ...

THE RELATIONSHIP of the thyroid gland to the severity of atheroselerosis in experimental animals has been clearly established,1 and the effects of hypothyroidism on cholesterol metabolism in man are well known.2 Although commonly affirmed in textbooks,3-5 there is still insufficient evidence that hypothyroidism in man aggravates the severity of atherosclerosis.6 Complementary evidence would be ...

Endemic goiter is a health problem in many areas of the world; in some areas the disease is so severe that cretinism and other defects are found. In many areas geographic, economic, and other factors prevent the use of iodized salt as a preventive measure. Field studies were begun in 1966 to determine the feasibility and effectiveness of parenteral administration of iodized oil in goiter prev...

In a survey of 974 villagers (408 males, 566 females; ages = 11-82 years) of the Ai (n = 496; 212 males, 284 females) and Lemanak (n = 478; 196 males, 282 females) rivers in the district of Lubuk Antu in Sarawak's Sri Aman Division during July 1993, goiter was found in 31.8% of the subjects. The goiter prevalence was higher in the more interior Ai river area than in the Lemanak river area (36.9...

Euthyroid multinodular goiters may lead to acute respiratory failure caused by airway obstruction or laryngotracheal compression. Here, we present a case admitted to the nephrologist with multinodular goiter spontaneous hemorrhage along with respiratory failure and end-stage renal disease (ESRD), which required urgent surgical intervention.We report the case of a 63-year-old woman with ESRD who...

UNLABELLED Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis and is involved in tumor development. To date, the role of VEGF in benign diseases of the thyroid is not well known. The purpose of the present study is to determine the expression of VEGF and its receptors in primary cultures of human thyrocytes. METHODS 50 patients with uninodular (n=11), multinodul...