The aim of this study was to improve the mucoadhesive potential of xyloglucan polymer by the covalent attachment of cysteine as thiol moiety. The parent polymer xyloglucan was chemically modified by introducing sulphydryl bearing compound L-cysteine HCl. Different batches of xyloglucan-cysteine conjugates were prepared at varying reaction pH (2-6) and evaluated for optimum thiol incorporation, ...

The title complex, [Fe2(C8H12S3)(CO)6] or [{Fe(CO)3}2(μ-L)] [L = 3,3-dimethyl-4-(propan-2-yl-idene)thietane-2,2-bis-(thiol-ato)], consists of two Fe(CO)3 moieties double-bridged by a di-thiol-ate ligand. Each of the two Fe(I) atoms has a distorted anti-prismatic coordination environment consisting of three carbonyl groups, two S atoms of the di-thiol-ate ligand and the neighboring Fe(I) atom [F...

The implication of mitochondrial protein thiols has been postulated in several functions: coupling mechanism, transport, conformations changes, dehydrogenases, etc.. A general review concerning these topics has been published recently [ 11. In order to localize these SH-groups it is necessary to evaluate the penetrability of SH reagents through the inner membrane; this was done by measuring, in...

Cyanylation of myosin with 6-thiol’4Clcyanato-9-/3-o-ribofuranosylpurine shows a biphasic effect. During the incorporation of the first 4 mol of cyanide the Mg”+-dependent ATPase activity increases approximately &fold, the Ca*+ activity rises only slightly, and the K+(EDTA) activity falls to approximately 5% of its original value. These enzyme preparations can still be inactivated by N-ethylmal...

In cells, the ratio/equilibrium between oxidized and reduced forms of glutathione and between cysteine and cystine (main cells antioxidants) affect thiol balance and redox status of cells and proteins (4). In general, spectroscopic and chromatographic methods are used for quantitative determination of low-molecular thiols and sulfhydryl groups in proteins. Optical methods are employed to detect...

despite the preventative and therapeutic effects of regular exercise, exhaustive exercise may be harmful to health. the present study aimed to determine the protective effect of endurance training and cinnamon bark extract (cbe) supplementation on oxidative responses induced by an exhaustive exercise schedule in rats. the rats were randomly divided into the following five groups of 6; control s...

The functionalization of elastomers by phosphonate groups remains relatively unexplored considering the great potential these polymers would represent for applications. In this paper, thiol-functional oligophosphonates were designed and coupled a thiol-ene reaction to styrene-butadiene rubber (SBR). We adopted RAFT methodology with dimethyl vinylphosphonate (DMVP) high-temperature thermolysable...

This article synthesized and characterized a novel antibacterial hydrogel, which is formed using maleimide–thiol conjugation. Two precursors chitosan functionalized thiol groups dextran maleimide prepared by Nuclear Magnetic Resonance (NMR). Key features of the such as gelation time, swelling behavior, viscoelastic properties, degradation rate, were thoroughly examined. From time result, we fou...

Purpose: Our study investigates the correlation between thiol/disulfide homeostasis and mortality among chronic obstructive pulmonary disease (COPD) patients with hypercapnic respiratory failure (HRF). Materials Methods: This cross-sectional prospective comprises a total of 104 subjects, including 64 HRF admitted to Emergency service due 40 healthy controls. were further divided into two subgro...

1,3-dimercaptopropan-2-ol, a symmetrical di-thiol, has been synthesized and applied as new type of anchor molecule to prepare self-assembled monolayer (SAM) on gold surface. The formed monolayers were studied by cyclic voltammetry, impedance spectroscopy, X-ray photoelectron kinetic capacitance, contact angle measurements. SAM structure depends the adsorption conditions. A short incubation time...