Linear oligomeric silsesquioxanes with polar side moieties (e.g., carboxylic groups and derivatives of N-acetylcysteine, cysteine hydrochloride or glutathione) can form specific, self-assembled nanostructures when deposited on mica by dip coating. The mechanism of adsorption is based on molecule-to-substrate interactions between carboxylic groups and mica. Intermolecular cross-linking by hydrog...

onychomycosis constitutes the most common fungal infection of nail affecting finger and toe nails as well. antifungals found to be effective in the treatment of onychomycosis. however, transport of oral antifungal agents exhibits more toxicity and requires longer treatment period. medicated nail lacquers proved to cause lesser toxicity and required shorter treatment period. it provides not only...

Thioglycolic acid (TGA) is the active ingredient of permanent-waving solution (PWS). TGA has been shown to be a chemical of high toxicity, which can be absorbed through intact skin and cause damage to organs or systems in animals. This study evaluated the effect of TGA-containing PWS on the health of a human population in 3 substudies. Firstly, 57 female hairdressers exposed to TGA-containing P...

Bromination of visnaginone (1) yielded the dibromo derivative (2), which upon methylation with methyl iodide gave 1-(2,7-dibromo-4,6-dimethoxybenzofuran-5-yl) ethanone (3). Compound (3) reacted with dimethylformamide dimethylacetal to give (4). The reaction of (3) with aromatic aldehydes namely (vanillin, benzaldehyde and 3-anisaldehyde) in ammonium acetate, malononitrile and/or butyric cyanoan...

Onychomycosis constitutes the most common fungal infection of nail affecting finger and toe nails as well. Antifungals found to be effective in the treatment of onychomycosis. However, transport of oral antifungal agents exhibits more toxicity and requires longer treatment period. Medicated nail lacquers proved to cause lesser toxicity and required shorter treatment period. It provides not only...

Bromide and thiocyanate have been shown to be effective inhibitors of the chlorination process leading to chlortetracycline formation by certain strains of Streptomyces aureofaciens Duggar (Gourevitch et al., 1955; Doerschuk, et at., 1956). Sekizawa (1955) reported thiourea, 2-thiouracil, 2-mercaptobenzothiazole, and thioglycolic-f3-aminonaphthalide (thionalide) to inhibit chlorination by this ...

BACKGROUND l-Arginine is a semi-essential aminoacid with important role in regulation of physiological processes in humans. It serves as precursor for the synthesis of proteins and is also substrate for different enzymes such as nitric oxide synthase. This amino-acid act as free radical scavenger, inhibits the activity of pro-oxidant enzymes and thus acts as an antioxidant and has also bacteric...