Two-in-one: Me3 SiCF2 Br is an efficient difluorocarbene source and is compatible with both neutral and aqueous basic conditions. Bromide-ion-initiated [2+1] cycloaddition with alkenes/alkynes and hydroxide ion promoted α-addition with (thio)phenols, (thio)alcohols, sulfinates, heterocyclic amines, and H-phosphine oxides give the corresponding gem-difluorinated compounds with broad functional-g...

In the title compound, C(15)H(15)N(3)OS, the thio-urea group is stabilized by an intra-molecular hydrogen bond between the carbonyl O atom and the thio-amide group. A C-H⋯N intramolecular hydrogen bond is also present. Mol-ecules are linked by inter-molecular N-H⋯O and C-H⋯S hydrogen bonds.

The title compound, C(16)H(12)N(2)O(2)S, was prepared by a Neigishi cross-coupling reaction to investigate the coordination chemistry of thio-phene-containing ligands. In the mol-ecule, the pyridine rings are twisted from the thio-phene ring by 20.6 (1) and 4.1 (2)°. The six-membered dihydro-dioxine ring is in a half-chair conformation.

In the title mol-ecule, C16H28O2S, the two n-hexyl groups are in all-trans conformations. Their C atoms are situated close to the plane of the thio-phene ring with a maximum deviation of 0.718 (6) Å for one of the terminal methyl groups. In the crystal, a short C-H⋯O contact is observed between thio-phene 1,1-dioxide groups.

Indoles substituted by electron-depleted thio groups at positions 1 and 3 react as C2 = C3 dipolarophiles with an electron-rich azomethine ylide dipole under flow conditions. The dearomatizing (3 + 2) cycloadditions readily occur to afford the corresponding fluorinated 3D-pyrrolidinoindolines bearing a tetrasusbtituted carbon centre ring junction.

Thiol-ene and thiol-yne photomediated conjugations have received substantial attention in research practice. Herein is presented the photodisulfidation of alkenes based on radical-mediated 1:1 reaction a disulfide vinyl ether, which provides an additional route for formation types sulfides seen thiol-ene polymers. Although similar linkages are formed, this approach starting with disulfides expe...