The stability of the drug actarit was studied under different stress conditions like hydrolysis (acid, alkaline and neutral), oxidation, photolysis and thermal degradation as recommended by International Conference on Harmonization (ICH) guidelines. Drug was found to be unstable in acidic, basic and photolytic conditions and produced a common degradation product while oxidative stress condition...

Due to the synergistic effect that occurs between CNTs and alumina, CNT/alumina hybrid-filled epoxy nanocomposites show significant enhancements in tensile properties, flexural thermal conductivity. This study is an extension of previously reported investigations into nanocomposites. A series composites with different loadings were investigated regard their thermal-degradation kinetics lifetime...

The moisture absorption behavior and the influence of moisture on thermal and mechanical properties of glass–fiber/polyetherimide (PEI) laminates have been investigated. The laminates were exposed to hydrothermal aging at two different temperatures and high moisture rates. The properties of as-received and hydrothermally aged samples were compared. The hydrothermally aged laminates contained a ...

A simple, sensitive and precise RP-HPLC-DAD method was developed and validated for the determination of olmesartan medoxomil (AT-II receptor blocker) in the presence of its degradation products. Olmesartan medoxomil and all the degradation products were resolved on a C(18) column with the mobile phase composed of methanol, acetonitrile and water (60:15:25, V/V/V, pH 3.5 by orthophosphoric acid)...

Piracetam was subjected to the hydrolytic, oxidative, thermal and photolytic stress, according to ICH guideline Q1A (R2). The drug depicted degradation only in basic conditions, while it was stable to other stress conditions (acidic, neutral hydrolysis, thermal and photolytic conditions). A total of one degradation product was formed, which were separated on a BEH column employing an isocratic ...

Nondestructive evaluation (NDE) methods are being developed for thermal barrier coatings (TBCs) and for gas-separation membranes. For TBC applications, current NDE development is focused on infrared thermal imaging methods. Compared with optical and other methods, thermal imaging is quantitative so can be used to characterize TBCs during their entire life cycle, from as-processed condition to s...

Effects of chain-end structure and residual metal compounds on thermal degradation of poly(epsilon-caprolactone) (PCL) were investigated by means of thermogravimetric and pyrolysis-gas chromatograph mass spectrometric analyses. Four types of PCL samples with different chain-end structures (alpha-carboxylic acid-omega-hydroxyl-PCL, alpha-dodecyl ester-omega-hydroxyl-PCL, alpha-carboxylic acid-om...

We have studied the wet thermal oxidation of In0.52Al0.48As and its potential application in current and optical confinement in vertical cavity surface emitting lasers VCSELs . Two types of InP-based heterostructures were used to study the effect of adjacent layer compositions on the lateral oxidation behavior of the InAlAs. It was found that the oxidation of In0.52Al0.48As with InP adjacent la...

This short Feature Article reviews electric stimuli-responsive polymer/clay nanocomposites with respect to their fabrication, physical characteristics and electrorheological (ER) behaviors under applied electric fields when dispersed in oil. Their structural characteristics, morphological features and thermal degradation behavior were examined by X-ray diffraction pattern, scanning electron mic...