Suppressed adaptive immune function is one of the major concerns responsible for the development of opportunistic infections and subsequent sepsis with high mortality in severe burns. Endoplasmic reticulum stress (ERS) is the endogenous self-protective mechanism, and it plays an important role in almost every process of living by regulating the balance between homeostasis and apoptosis. The cur...

BACKGROUND Accurate determination of the depth of burn injury is difficult, even for experienced surgeons. The authors hypothesized that the level of plasma free hemoglobin following burn injury is correlated to the depth of burn injury, and they evaluated this hypothesis in a murine model. METHODS Full-thickness and partial-thickness burn injuries of varying sizes were inflicted on 38 and 36...

OBJECTIVE To assess the efficacy of Aloe Vera gel compared with 1% silver sulfadiazine cream as a burn dressing for the treatment of superficial and partial thickness burns. METHODS This Interventional Comparative study was carried out at the Burn unit and Plastic surgery department, Nishtar Hospital Multan, Pakistan from July 2008 to December 2010. A total of 50 patients with superficial and...

Burns from domestic electric irons are a potentially preventable injury which can result in considerable morbidity. Surface temperatures of electric irons can reach in excess of 200 ̊C, meaning that contact for even brief periods can cause a significant thermal injury. Several previous studies have described contact burns from irons in paediatric populations 7 and have discussed various methods ...

Burn care is one of the few areas in medicine considered both medically and surgically challenging, with burn injuries affecting people of all ages and both sexes. Between May 1992 and March 2012, 1,524 patients were admitted to the Lebanese Burn Center in Geitawi, with an average length of stay (LOS) of 36.5 days. The most frequently encountered injuries were thermal burns, generally resulting...

The treatment of chronic wounds, burns and scars is not easy to solve, because the most suitable dressing for wound care depends not only on the type of wound but also on the stage of the healing process. Wound dressing have been employed to speed up the healing process in acute and chronic wounds by keeping healing tissues moist and increasing superficial wound epithelialization [1,2]. Apart o...

Moxibustion strengthens immunity and it is an effective treatment modality, but, depending on the material quantity, shape, and composition, the thermal strength and intensity can be difficult to control, which may cause pain or epidermal burns. To overcome these limitations, a heat stimulating system which is able to control the thermal intensity was developed. The temperature distributions on...

abstractbackgroundcontributes substantially to patient morbidity and mortality.in this study we investigatedthe range and distribution of t-lymphocyte. subsets cd3helper/inducer cell,.th ), cd8: severe immunosuppression occurs after large thermal burn and probably+ (t cells) cd4+ (t+ (t suppressor /cytotoxic cells ,ts/c), cd3+cd4thermal injury.+/cd3+cd8+ ratio, cd19+ (b cells) and cd16+ (nk cel...