Recent X-ray and weak-lensing observations of galaxy clusters have revealed that the hot gas does not always directly trace the dark matter within these systems. Such configurations are extremely interesting. They offer a new vista onto the complex interplay between gravity and baryonic physics, and may even be used as indicators of the clusters’ dynamical state. In this paper, we undertake a s...

Aims: To present 12 new variants of uracil mustard having drug-like properties and cytotoxic functional group, by utilizing uracil mustard (uramustine) as a lead compound. Utilize rigorous substructure and similarity of a molecular scaffold to determine drug like variants. Physicochemical properties determined indicate the variants have favorable drug-likeness. Study Design: Conduct molecular d...

The Smaller Intracerebral Vessels • A pathological study of the smaller intracerebral arteries of 150 to 600 /A was made in 336 cases, ranging in age from 1 day to 96 years. The changes involved the media and adventitia in contradistinction to the large cerebral vessels which showed predominantly intimal changes. The degree of change in the smaller intracerebral arteries was age related but not...

as technology scales deep into the nanometer regime, on-chip communication becomes more susceptible to transient noise sources, such as crosstalk, external radiation, and spurious voltage spikes. the network on chip s modularity and reusability has brought about the use of error control methods to address transient errors in network on chip links.in this work, we design a fault tolerance router...

This study focuses on the effects of elevated building substructure porosity on the accumulation of drifting snow. We conducted wind tunnel experiments of the snowdrift accumulation and numerical simulations to determine the flow field around a prototypical elevated building (based on the Martin A. Pomerantz Observatory or MAPO) with varying substructure porosity. We found that the total drift ...

In the past decade, surveys of the stellar component of the Galaxy have revealed a number of streams from tidally disrupted dwarf galaxies and globular clusters. Simulations of hierarchical structure formation in ΛCDM cosmologies predict that the dark matter halo of a galaxy like the Milky Way contains hundreds of subhalos with masses of ∼ 10 M⊙ and greater, and it has been suggested that the e...