Here we present computational machinery to efficiently and accurately identify transposable element (TE) insertions in 146 next-generation sequenced inbred strains of Drosophila melanogaster. The panel of lines we use in our study is composed of strains from a pair of genetic mapping resources: the Drosophila Genetic Reference Panel (DGRP) and the Drosophila Synthetic Population Resource (DSPR)...

Thermal infrared (IR) radiances measured near 8 microns contain information about the vertical distribution of water vapor (H2O), the water isotopologue HDO, and methane (CH4), key gases in the water and carbon cycles. Previous versions (Version 4 or less) of the TES profile retrieval algorithm used a “spectral-window” approach to minimize uncertainty from interfering species at the expense of ...

Transposable elements (TEs) account for a large portion of the genome in many eukaryotic species. Despite their reputation as "junk" DNA or genomic parasites deleterious for the host, TEs have complex interactions with host genes and the potential to contribute to regulatory variation in gene expression. It has been hypothesized that TEs and genes they insert near may be transcriptionally activ...

Investigating spatial patterns of loci under selection can give insight into how populations evolved in response to selective pressures and can provide monitoring tools for detecting the impact of environmental changes on populations. Drosophila is a particularly good model to study adaptation to environmental heterogeneity since it is a tropical species that originated in sub-Saharan Africa an...

The aphorism “A mind is a terrible thing to waste” ppears to be the impetus behind a proposal (Krause and ohen Kadosh, 2013) to extend the techniques of transcraial electrical stimulation (TES) to children. This suite of echniques have attracted a great deal of interest amongst hose interested in using them to modify adult brain funcion, but as the authors point out, pediatric use of TES as bee...

Penilaian berusaha menentukan apakah tujuan pendidikan tercapai atau tidak, sehingga evaluasi memiliki peran yang sangat besar dunia pendidikan. Setiap mata pelajaran menekankan berkesinambungan, mengacu pada dan hasil komprehensif. Adapaun diantara ranah penilain dalam adalah kognitif.Penilaian kognitif merupakan kegiatan dilakukan untuk mengukur penguasaan pengetahuan peserta didik. Tujuan pe...

The distribution of transposable elements (TEs) in a genome reflects a balance between insertion rate and selection against new insertions. Understanding the distribution of TEs therefore provides insights into the forces shaping the organization of genomes. Past research has shown that TEs tend to accumulate in genomic regions with low gene density and low recombination rate. However, little i...

PURPOSE The purpose of this study was to determine the potentialof cancer testis (CT) antigens as vaccines for non-Hodgkin's lymphomas (NHLs). EXPERIMENTAL DESIGN Ninety-three specimens of NHLs were analyzed for their composite expression of eight CT genes (MAGE-3, MAGE-4, CT-7, HOM-MEL-40/SSX-2, SSX-1, SSX-4, HOM-TES-14/SCP-1, and HOM-TES-85). Thirty-nine of these specimens were also analyze...

TEStool is a visual interactive software environment for modeling autocorrelated time series, using a versatile class of stochastic processes called TES (Transform-Expand-Sample). The novel feature of the TES modeling approach is that it strives to t a model to empirical records by simultaneously capturing both the empirical distribution and the leading empirical autocorrelations. Thus, TES mod...

Concurrent tropospheric O 3 and CO vertical profiles from the Tropospheric Emission Spectrometer (TES) during the MILAGRO/INTEX-B aircraft campaigns over the Mexico City Metropolitan Area (MCMA) allow us to characterize mega-city pollution. Outflow from the MCMA occurred predominantly at 600–800 hPa, evident in O 3 , CO, and NO x 5 enhancements in the in situ observations. We examined O 3 , CO,...