A serine Kunitz protease inhibitor was isolated from the semi-mature leaves of Terminalia arjuna, a host plant for Antheraea mylitta, using ammonium sulphate fractionation, gel permeation chromatography and trypsin–sepharose affinity chromatography. A 29-fold purification of T. arjuna Trypsin Inhibitor (TaTI) with a yield recovery of 3.2% was achieved. The purified protease inhibitor (TaTI) was...

Diarrhoeal illness remains a key global health problem causing 15% of deaths among children under five years age. This study evaluated the antidiarrhoeal activity Terminalia catappa aqueous stem bark extract on albino rats. Antidiarrhoeal T. was assessed by measuring stool inhibition, gastrointestinal motility and castor oil-induced enteropooling. Thirty (30) rats were divided into 6 groups 5 e...

A total of 115 different plant extracts from our collection, representing 96 plant species, have been evaluated for in vitro antileishmanial activity against L. amazonensis promastigotes. In addition, the extracts were screened for cytotoxic activity against BALB/c mouse macrophages in order to assess a selectivity index. Crude extracts that showed a selectivity index (CC50 for macrophage / IC5...

Numerous herbs have been used successfully in treating dermatologic disorders for thousands years and still widely used because it is easy to find, cheap and to avoid the side effects and complications of topical steroids. Terminalia chebula, commonly found in India and Southeast Asia, is thought to be effective for treating several diseases including inflammation and reported as an anti-oxidan...

Terminalia belerica (behada) fruit has been evaluated as a promising agent against E. histolytica and a variety of bacteria associated with dysentery and diarrhoea. These in vitro studies were extended further for evaluating clinical efficacy among patients of acute and chronic cases of diarrhoea and dysentery. The Studies were carried out on 25 patients by five medical practitioners practicing...

In this research work, the antioxidant and metabolomic profiling of seven selected medicinally important herbs including Rauvolfia serpentina, Terminalia arjuna, Coriandrum sativum, Elettaria cardamom, Piper nigrum, Allium sativum, and Crataegus oxyacantha was performed. The in vivo cardioprotective potential of these medicinal plants was evaluated against surgically induced oxidative stress th...