BACKGROUND Aromatherapy and hand massage therapies have been reported to have some benefit for people with dementia who display behavioural symptoms; however there are a number of limitations of reported studies. The aim is to investigate the effect of aromatherapy (3% lavender oil spray) with and without hand massage on disruptive behaviour in people with dementia living in long-term care. M...

OBJECTIVE Suicide risk is highest in later life; however, little is known about the risk of suicide among older adults in long-term care facilities (e.g., nursing homes and assisted living facilities). The goal of this paper is to review and synthesize the descriptive and analytic epidemiology of suicide in long-term care settings over the past 25 years. METHODS Four databases (PubMed, CINAHL...

In normal animals, operant conditioning of the spinal stretch reflex or the H-reflex has lesser effects on synergist muscle reflexes. In rats and people with incomplete spinal cord injury (SCI), soleus H-reflex operant conditioning can improve locomotion. We studied in normal humans the impact of soleus H-reflex down-conditioning on medial (MG) and lateral gastrocnemius (LG) H-reflexes and on l...

Bougainvillea (Bougainvilleaspectabilis) is used for planting in the landscape because of their beautiful and colorful flowers. The easiest and cheapest technique to propagate this plant is by cuttings; however the cuttings of this plant are not easily rooted and require the special treatments, including the use of auxin. For this purpose, an experiment was performed in Completely Rand...

Long-term potentiation (LTP) is a use-dependent form of synaptic plasticity that is of great interest as a cellular mechanism that may contribute to memory storage. It is the sustained phase of population excitatory postsynaptic potential induced by high-frequency stimulation (HFS). HFS can also induce short-term potentiation (STP), a decremental potentiation lasting approximately 15 min. It ha...

Background: The Diabetes Care Program of Nova Scotia (DCPNS) works across various sectors of the health care system to improve the care provided to people with or at risk of developing DM. The lack of evidenced-based DM guidelines for the elderly population has resulted in both under and over treatment of the frail elderly residing in NS’s long-term care (LTC) facilities. Overtreatment may resu...

OBJECTIVE To investigate the effect of neurogulin-1 (NRG1) on the transmission and plasticity of CA1 synapses in mouse hippocampal slices at different temperatures. METHODS Under room temperature (26-/+1 degrees C) or physiological temperature (32-/+1 degrees C), field excitatory postsynaptic potential (fEPSP) evoked by extracellular microelectrode recording technique was recorded in the CA1 ...

We uncovered a role for ERK signaling in GABA release, long-term potentiation (LTP), and learning, and show that disruption of this mechanism accounts for the learning deficits in a mouse model for learning disabilities in neurofibromatosis type I (NF1). Our results demonstrate that neurofibromin modulates ERK/synapsin I-dependent GABA release, which in turn modulates hippocampal LTP and learni...

transluminal balloon valvuloplasty is an alternative to surgical valvotomy for congenital pulmonary valve stenosis. the aim of this study was to evaluate the long term results (to 13.5 years) of balloon pulmonary valvuloplasty. from june 1998 to january 2012, percutaneous balloon pulmonary valvuloplasty for congenital pulmonary valve stenosis was performed in 98 patients (50 males, 48 females, ...