Teratozoospermia is a disorder associated with high abnormal sperm morphology which affects fertility in males. In recent years, it has been described that biomarker-based sperm quality evaluation can alleviate male infertility treatment. Phospholipase C zeta (PLCζ) is a sperm-specific factor which appears to be a predicting biomarker for fertilization potential of males. Following fertilizatio...

The aim of this study was to determine whether sperm morphology and nuclear maturity are associated with an increase in the prevalence of disomy in human spermatozoa. Semen samples were obtained from 60 patients selected at random from a population of men undergoing semen analysis as part of consultation for infertility. Semen analysis and aniline blue staining were carried out on each ejaculat...

Globozoospermia is a severe form of teratozoospermia characterized by round-headed spermatozoa with an absent acrosome, an aberrant nuclear membrane and midpiece defects. Globozoospermia is diagnosed by the presence of 100% round-headed spermatozoa on semen analysis, and patients with this condition are absolutely infertile. The objective of this study was to investigate the differences in prot...

Assisted oocyte activation (AOA) is the technique that simulates the effect of sperm penetration into an oocyte inducing oocyte activation. This technique is used in combination with intracytoplasmic sperm injection (ICSI) to improve the outcome of the fertilization process. It is mostly beneficial and recommended in those cases, when classic ICSI fails. This accounts approximately up to 5 % of...

OBJECTIVE To evaluate the ultramorphologic sperm features of idiopathic infertile men after acupuncture therapy. DESIGN Prospective controlled study. SETTING Christian-Lauritzen-Institut, Ulm, IVF center Munich, Germany, and Department of General Biology, University of Siena, Siena, Italy. PATIENT(S) Forty men with idiopathic oligospermia, asthenospermia, or teratozoospermia. INTERVENTI...

Infertility affects about 15 per cent married couples half of which may be attributed to men with low sperm motility (asthenozoospermia), low sperm count (oligozoospermia) or abnormal sperm morphology (teratozoospermia). As mitochondria are the energy source for initiation, differentiation and function of the germ cells, mutation in mitochondrial genome can impair the formation of mature sperma...

BACKGROUND Globozoospermia is a severe form of teratozoospermia (incidence < 0.1%) in infertile men that is characterized by round headed sperm and acrosomeless in semen. OBJECTIVE To compare the semen parameters, protamine deficiency, and apoptosis in ejaculated spermatozoa between globozoospermic and normozoospermic men. MATERIALS AND METHODS Thirty six semen samples were divided into two...

BACKGROUND Erroneous diffusing capacity of the lung for carbon monoxide (Dlco) values as measured by spectrophotometry were observed at our facility in ethanol-intoxicated subjects. An atypical methane curve tracing was noted in these subjects. STUDY OBJECTIVES We hypothesized that ethanol intoxication interferes with Dlco measurements obtained using methane and designed a study to assess the...

FIGURE 1: Clinically normal 18-year-old girl. T HE SERIAL TRACINGS TAKEN 15 MINutes apart are from a clinically normal 18-year-old girl with an innocent heart murmur. The initial resting electrocardio-gram (Fig. 1) is abnormal because of the low voltage of all T waves, with definite inversion of T in V3. Fifteen minutes later, the tracing was repeated and normal T waves are present (Fig. 2). Bo...

The semen quality during the low (May-July) and the peak (September-November) breeding seasons in 18 Nili-Ravi buffalo bulls varying in age from 3 to 15 years was studied. Ejaculatory volume was higher (P < 0.05) in adult (3.03 ± 0.13 ml) and old (2.86 ± 0.13 ml) than young (2.51 ± 0.11 ml) bulls and during the low (3.44 ± 0.11 ml) than the peak (2.57 ± 0.90 ml) breeding season. Mass activity o...