نتایج جستجو برای: target conjugate
تعداد نتایج: 437160 فیلتر نتایج به سال:
The spontaneous natural killer (NK) and lymphokine-activated killer (LAK) cytotoxicity of highly purified CD56+CD3- NK cells (90 to 95%) against NK-sensitive and NK-insensitive target cells was drastically enhanced when a rhamnogalacturonan contained in a commercially available Viscum album extract was present during 4-h cytotoxicity assays. This enhancement correlated strictly with an increase...
BACKGROUND Functionalized gold nanoparticles are emerging as a promising nanocarrier for target specific delivery of the therapeutic molecules in a cancer cell, as a result it targeted selectively to the cancer cell and minimized the off-target effect. The functionalized nanomaterial (bio conjugate) brings novel functional properties, for example, the high payload of anticancer, antioxidant mol...
Site-specific DNA binding molecules offer the potential for genetic manipulation of mammalian cells. Peptide nucleic acids (PNAs) are a DNA mimic in which the purine and pyrimidine bases are attached to a polyamide backbone. PNAs bind with high affinity to single-stranded DNA via Watson-Crick base pairing and can form triple helices via Hoogsteen binding to DNAPNA duplexes. Dimeric bis-PNAs cap...
A conjugate heat transfer investigation was conducted to better understand the effects of an impinging radial slot jet cooling device on both the heat transfer rates and temperature fields in the fluid, and especially in the cylindrical solid cooled by this device. Such temperature nonuniformities in the solid are of practical interest as they may result in phenomena such as nonuniform material...
In [1] (Hybrid Conjugate Gradient Algorithm for Unconstrained Optimization J. Optimization. Theory Appl. 141 (2009) 249 - 264), an efficient hybrid conjugate gradient algorithm, the CCOMB algorithm is proposed for solving unconstrained optimization problems. However, the proof of Theorem 2.1 in [1] is incorrect due to an erroneous inequality which used to indicate the descent property for the s...
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