OBJECTIVE This study aimed to determine whether anti-rK39 antibodies were diagnostic markers for visceral leishmaniasis (kala-azar) and to evaluate the correlation between age and gender in disease occurrence in Iraqi patients. In addition, it aimed to evaluate the correlation between thyroid hormones, i.e., thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) and anti-r...

the study was conducted to evaluate the effect of different levels of synthetic lysine (slys) on dry matter intake (dmi), average daily weight gain (adg), dry matter conversion ratio (dmcr), carcass characteristics and economics of productionof finisher broiler chicks. as 240 day-old broiler chicks were randomly distributed to 12 pens of 20 chicks each and assigned to four treatment rations in ...

Thyroid gland is an essential endocrine that present in the human body. This review highlights production, regulation and disease conditions of thyroid hormones. The controlled with help hypothalamus pituitary brain. production hormones involves five main steps such synthesis thyroglobulin (TG), iodide uptake, iodination thyroglobulin, storage release. two important produced by are Thyroxine (T...

A possible metabolic linkage between hepatic thyroxine (T4) 5'-deiodination and the NADPH-glutathione (GSH) cycle was studied in rat liver. Supplementation of 1 mM NADPH to stocked liver homogenates in vitro produced 4 fold increase in 3, 5, 3'-triiodothyronine (T3) formation from T4, whereas the effect of 1 mM FMN, FDN, NAD, NADH, or GSH was relatively small. An exponential dose-response relat...

This study was designed to determine the effect of increase hyperthyrodisim on some hormones (Triiodothyronine, thyroxin, thyroid stimulating hormone) and biochemical parameters (creatinine, magnesium) 58 sample used in this at age (25-40 years), where samples were divided into two groups a rate 29 per group. The totals as follows: control group, group patients. It measured hormone Triiodothyro...

Changes in TSH secretion in six acromegalic patients were studied before and after transsphenoidal adenomectomy (Hardy's method) and compared to normal subjects and six patients with prolactinoma. Basal serum GH levels ranging from 5 to over 250 ng/ml before adenomectomy decreased to below 5 ng/ml after the operation, and the abnormal responses of GH to TRH observed initially in three of the si...

BACKGROUND AND PURPOSE Low level of thyroid hormone is a strong independent risk factor for white matter (WM) injury, a major cause of cerebral palsy, in preterm infants. Thyroxin upregulates brain-derived neurotrophic factor during development. We hypothesized that thyroxin protected against preoligodendrocyte apoptosis and WM injury in the immature brain via upregulation of brain-derived neur...

The effects of thyroid hormone analogues on modulation of angiogenesis have been studied in the chick chorioallantoic membrane model. Generation of new blood vessels from existing vessels was increased 3-fold by either l-thyroxine (T4; 10(-7) mol/L) or 3,5,3'-triiodo-l-thyronine (10(-9) mol/L). T4-agarose reproduced the effects of T4, and tetraiodothyroacetic acid (tetrac) inhibited the effects...

The nervous system is dependent upon thyroid hormones for normal development, and we previously reported that developmental Aroclor 1254 (A1254) exposure caused hypothyroxinemia, hearing loss and other behavioral changes in rats. (Goldey et al., 1995a; Herr et al., 1996). The hypothesis that A1254-induced hypothyroxinemia may have contributed to the observed functional changes was tested in pri...

BACKGROUND A recent randomized controlled trial suggests that hypothyroid subjects may find levothyroxine (l-T4) and levotriiodothyronine combination therapy to be superior to l-T4 monotherapy in terms of quality of life, suggesting that the brain registered increased T3 availability during the combination therapy. HYPOTHESIS Peripheral tissue might also be stimulated during T4/T3 combination...