BACKGROUND It is generally accepted that emphysematous lungs are characterized by an increase in the numbers of neutrophils, macrophages, and CD8+ T lymphocytes, the lasts having increased cytotoxic activity. Because systemic inflammation is also a component of emphysema, we hypothesize that peripheral CD8+ T lymphocytes of emphysematous smokers who show evidence of systemic inflammation will h...

Rosettes formation technique (SRBC) was employed for the assessment of lymphocyte per cent. Development of accurate methods for enumeration of T and B lymphocytes in human and animal peripheral blood during the past decades has led to a plethora of papers on T and B lymphocytes in various pathologic states. Lymphocytes can be divided into T and B lymphocytes on the basis of selective binding ca...

T lymphocytes from a majority of patients with urogenital gonococcal disease (67%-80%) proliferated on incubation with gonococcal porin (Por), compared with minimal induced proliferation of T lymphocytes from normal volunteers. A significant increase in Por-specific interleukin (IL)-4-producing CD4+ T helper lymphocytes was seen in patients with mucosal gonococcal disease and not in normal cont...