BACKGROUND Dual-chamber pacing can improve symptoms in hypertrophic cardiomyopathy (HCM), but the mechanism remains unclear. We hypothesized that pacing generates discoordinate contraction and a rightward shift of the end-systolic pressure-volume relation (ESPVR) and that benefits from this mechanism do not depend on the presence of resting outflow pressure gradients or obstruction. METHODS A...

the purpose of this study is to survey cross section changes of the animal brain samples during the tension and compression tests and comparison of the experimental results for three animals: bovine, sheep, and rabbit. a linear elastic theory with considering the necking in tension and barreling in compression has been considered for brain tissue. bridgman method for tension and cross section u...

BACKGROUND Biventricular direct cardiac compression (DCC) has the potential to support the failing heart without the complications associated with a blood/device interface encountered with the use of current ventricular assist devices. A clinically designed DCC device that provides compression pressure around the base of the heart in synchrony with native ventricular contractions was evaluated ...

PURPOSE To describe the mechanisms of hemodynamic changes during off-pump coronary artery bypass graft surgery (OP-CABG). SOURCE Pertinent medical literature in the English and French languages was identified through a Medline computerized literature search and a manual search of selected articles, using off-pump coronary artery surgery, beating heart surgery, hemodynamic, and transesophageal...

The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...

To test the hypothesis that fluctuations in global intrathoracic pressure are the dominant cause of blood flow during external cardiopulmonary resuscitation (CPR) the authors studied the effects of open pneumothorax on experimental CPR in 7 domestic pigs and 12 mongrel dogs. Similar studies were conducted independently at three laboratories and are reported jointly. All studies were conducted d...

BACKGROUND The presence of a myocardial bridge (MB) has been shown to promote atherosclerotic plaque formation proximal to the MB, presumably because of hemodynamic disturbances provoked by retrograde blood flow toward this segment in cardiac systole. We aimed to determine the anatomic and functional properties of an MB related to the extent of atherosclerosis assessed by intravascular ultrasou...

the dried fruit of terminalia chebula is widely used for its laxative properties. the objective of the present study was to examine the flowability and compressibility of terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. initial studies on flowability and compressibility revealed that the fruit powder...

background and aims: neurons are injured under physical, chemical and pathological conditions. the effect of peripheral nervous system injuries may return as retrograde to the cell body of neurons in central nervous system resulting in brain and spinal cord degeneration. because of high content of camphor and borneol, achillea biebersteinii from asteracea family may be effective in prevention t...