Technologies and cancer therapies develop at a rapid pace, which makes staying current with changes diffi cult for nurses. Newer cancer modalities combine surgery or interventional radiology techniques to deliver regional chemotherapy, limiting systemic toxicities. Chemotherapy-certifi ed nurses must be available to assist with chemotherapy administration in nontraditional areas. This article p...

Pancreatic cancer is one of common malignant neoplasms. It characterized by poor prognosis and high mortality, which mainly due to detection in an advanced stage. This review presents epidemiological clinical characteristics pancreatic cancer, as well current strategies systemic treatment disease, including first- second-line chemotherapy, molecularly targeted therapies immunotherapy.

objective primary central nervous system lymphoma (pcnsl) is an extremely rare condition in childhood. we report the first case of pcnsl in a child in iran. clinical presentation a nine-year-old boy was referred to mofid hospital with the history of headache of four months and seizure of 2 months duration. magnetic resonance imaging of the brain revealed a hyper-intense lesion in left fronto-pa...

BACKGROUND The management of asymptomatic primary tumor in patients with unresectable metastatic colorectal cancer remains inconsistent. OBJECTIVE This study aimed to determine the rate of symptom-directed surgery after systemic chemotherapy and to estimate the impact of initial primary tumor resection on survival in patients with unresectable metastatic colorectal cancer and an asymptomatic ...

UNLABELLED Stage IV non-small cell lung cancer is a fatal disease, with a median survival of 14 months. Systemic chemotherapy is the most common approach. However the impact in overall survival and quality of life still a controversy. OBJECTIVES To determine differences in overall survival and quality of life among patients with stage IV non-small cell lung cancer non-metastatic to the brain ...

If one was a surgeon who believed in postoperative systemic chemotherapy, one’s argument would be based on the results of the study GOG 172 (which coincided with a clinical alert from the NCI of the United States in favor of this modality of intraperitoneal treatment after optimal surgery in patients with ovarian cancer) [1]. According to the paper published by Armstrong et al, our relative wou...

We report two cases of liver metastases from colorectal and anal cancers after the failure systemic chemotherapies that were successfully treated with a combination therapy transarterial chemoembolization using irinotecan-loaded drug-eluting beads hepatic arterial infusion chemotherapy. In both cases, chemotherapy was performed as maintenance beads. Irinotecan at dose 120 mg loaded on drug deli...

The survival of most patients with both unresectable hepatic and pulmonary metastases of colorectal cancer is poor. In this retrospective study, we investigated the efficacy of computed tomography (CT)-guided radiofrequency ablation (RFA) and systemic chemotherapy plus hepatic artery infusion of floxuridine (HAI-FUDR). Sixty-one patients were selected from 1,136 patients with pulmonary and hepa...

We treated a patient with lung cancer in whom a hypercoagulopathy was induced acutely by chemotherapy. He received systemic chemotherapy twice and in both instances developed disseminated intravascular coagulopathy (DIC), accompanied by acute decrements of the peripheral platelet count and plasma fibrinogen, an increment of the fibrin degradation products (FDP), and bleeding tendency with the a...