background: recent accumulated evidence suggests that prolactin (prl) is an important immunomodulator and plays an important role in the pathogenesis of systemic lupus erythematosus (sle). the current study aimed to compare hyperprolactinemia frequency and evaluate its possible association with lupus activity in sle patients in zahedan. methods: in a case-control study we determined serum prola...

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the increasing incidence of systemic candidiasis, which parallels the use of invasive and immunosuppressive medical procedures, necessitates development of rapid and cost effective tests for diagnosis of systemic candidiasis. therefore in this study 85 mice were first immunosuppressed by cyclophosphamide and then infected by candida albicans ncpf 3153. other 85 mice were employed as control. th...

Nocardiosis is a rare infection that in more frequent in patients with systemic lupus Erythematosus and its clinical manifestations are nonspecific.while concurrent treatment by corticosteroids is an independent risk factor for nocardiosis it increases both diagnostic and mangement problems.this article presents a 35 years old woman who has systemic lupus Erythematosus.she was hospitalized due ...

Systemic drugs are used in the treatment of several skin diseases. In order to obtain best therapeutic results and prevent side effects, the patients should be carefully screened before and thoroughly evaluated during treatment. In this article guidelines for selection and follow up of patients receiving systemic drugs for their skin diseases are presented. These drugs include azathioprine, ant...