a simple and efficient method for synthesis of tetrahydropyrimido[4,5-b]quinoline derivatives via three component reaction of aromatic aldehydes, dimedone and 6-amino uracil derivatives using a catalytic amount of sulfonic acid functionalized nanoporous silica (sba-15-pr-so3h) is described. the advantages of this method are easy and clean work-up, high yield, mild reaction condition, reusable c...

1,2-diketones have been reacted in one-pot method with 1,2-diamines at room temperature with zno nanoparticles as a catalyst. zno nanoparticles as an available and reusable catalyst is used for the synthesis of quinoxalinein improved yields.

Escherichia coli is generally impermeable to charged molecules for which it does not possess specific transport mechanisms (2). This permeability barrier is thought to be the cause of the resistance of E. coli to actinomycin, since this antibiotic inhibits deoxyribonucleic acid (DNA)dependent ribonucleic acid (RNA) synthesis in in vitro extracts prepared from E. coli, but has no effect on RNA s...

Some 3, 5-diacyl or 3,5-diester 1,4-dihydropyridines were oxidized to the corresponding pyridine derivatives using hydrogen peroxide in aqueous ethanol in the presence of potassium bromide and acetic acid as the catalysts. The reaction was carried out in ethanol and products were isolated in high to excellent yields. However, oxidation of 3,5-diacetyl 1,4-dihydropyridines is slower than 3,5-die...

a simple, fast, efficient and environmentally friendly method for synthesis of benzimidazole and its 2-alkyl, aryl and heteroaryl substituted derivatives was developed using zeolite hy. two component cyclolcondensation of 1,2-phenylenediamine (o-phenylenediamine) and commercially available carboxylic acids catalyzed by zeolite hy without any solvent, under microwave irradiation led to formation...

lithium disilicate nano-powders were synthesized via a mild condition hydrothermal reaction at 180 ºc for 48 and 72 h with a non stoichiometric1:2 li:si molar ratio in naoh aqueous solution using li2co3 and sio2.h2o as raw materials. the synthesized materials were characterized by powder x-ray diffraction (pxrd) technique and fourier transform infrared (ftir) spectroscopy. the xrd data showed t...

Quinazolinone derivatives are essential units in a wide range of relevant pharmacophores with a broad spectrum of abilities. Due to their wide range of pharmacological and therapeutic activities including anticonvulsant, anti-inflammatory, hypolipidemic, anticancer, and anti-ulcer, the synthesis of quinazolinone moieties as a privileged class of fused heterocyclic compounds, have received much ...

in the present study, effects of iron excess treatments (0, 250, 500 mg l-1) were evaluated in four rice varieties including shafagh, khazar, hashemi and sadri in pot condition. afterward, effects of iron excess (10 and 250 mg l-1) were further investigated in the most resistant variety (shafagh) in sand culture with yoshida nutrient solution. this experiment was arranged as factorial in rcbd w...

Omeprazole, (6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzimidazole is a well-established prescribed drug, exhibits proton pump inhibitor activity. In this work, a novel, facile, economical and selective oxidation approach using H3PW12O40 as Keggin type heteropolyacids along with H2O2 in the ...

A convenient synthetic method for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetra substituted imidazole derivatives, has been developed via one-pot condensation reaction in solvent-free condition when aldehyde, ammonium acetate/amine, and 1,2-diketone are reacted using 0.8 mol% of NP-LaMnO3 at 80 °C under solvent free conditions. Catalyst could be recovered and reused in five reaction c...