The search for the precursor of invasive prostatic adenocarcinoma has intensified in recent years, focusing on the spectrum of histopathologic changes referred to as high-grade prostatic intraepithelial neoplasia. This microscopic finding, considered to be the most likely precursor of invasive carcinoma (7), is characterized by cellular proliferations within pre-existing ducts and glands, with ...

Non-traumatic ureteral rupture has been reported more frequently, resulting from increased intraluminal pressures from distal urinary tract obstruction. We report the case of a 77-year-old man presenting with chronic urinary retention secondary to massive prostatic enlargement through acute kidney injury. Ultrasound scan detected a shallow left perinephric fluid collection with a possible bladd...

BPH is characterized by enlargement of prostatic nodules due to a proliferative process involving both the stromal and epithelial elements of the prostate. As the prostate enlarges, the surrounding tissue offers resistance, causing the prostate to press against the urethra. Over a period of time, the urinary bladder wall becomes thicker, sensitive irritation and the bladder begins to contract e...

PURPOSE We attempted to improve the method of objective clinical evaluation of patients with benign prostatic enlargement and lower urinary tract symptoms. MATERIALS AND METHODS We compared the results of free uroflowmetry and transrectal ultrasound prostate size determination with those of pressure-flow analysis of bladder outlet obstruction in 871 consecutive elderly men. RESULTS Maximal ...

Prostatic enlargement due to benign adenomatous hyperplasia is very common in elderly males. However, benign mesenchymal tumors especially true leiomyoma of the prostate are rare. We describe a 68-year-old male presenting a urinary obstruction lasting more than two years. The patient was referred for an acute urinary retention. The clinical examination was normal. The perrectal examination reve...

Parkinson's disease (PD) typically manifests with asymmetric motor symptom onset. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with cognitive decline in PD, but not with motor symptom asymmetry. Asymmetrical ventricular enlargement on magnetic resonance images was explored in a monozygotic twin pair discordant for PD and in nine healthy monozygotic twin p...

prostatic intra-epithelial neoplasia (pin) is considered a precursor of invasive carcinoma, characterized by proliferation and anaplasia of cells lining prostatic ducts and acini. in this study, we applied the pin grading system on one-hundred cases of prostatic carcinoma and one-hundred cases of benign prostatic hyperplasia, then compared the results. 74% of prostatic carcinoma and 51 % of pro...

A 2750 g female infant presented with multiple striking 1-6 mm purpuric, non-blanching macules Blueberry-Muffin rashes. After symptomatic treatment, the whole body skin rash were scabby, liver and spleen were also moderately enlargement. The diagnosis was confirmed by skin biopsy. The parents were reluctant to use hormone therapy, and discharged against medical advises 21 days after admission.

We report a case of primary diffuse large B-cell lymphoma of the prostate in a 54-year-old Caucasian male who presented with urinary retention and benign prostatic hyperplasia. We discuss the rare presentation of this disease and its clinicopathologic features and review the literature for up-to-date information on the diagnosis and clinical management. Despite the low incidence of lymphoma inv...