BACKGROUND Analysis of the burden of gastro-oesophageal reflux disease (GERD) in relation to the severity and frequency of symptoms is essential to identify individuals and groups in whom targeted management is justified. AIM To describe the relationship between symptoms of GERD and self-reported health-related quality of life (HRQL), work productivity, healthcare utilization and concomitant ...

Introduction Gastrointestinal symptom-specific anxiety and somatisation have both been associated with higher symptom severity in patients irritable bowel syndrome (IBS). However, the relationship between these two factors IBS has not explored fully. In addition, performance of instrument that measures gastrointestinal anxiety, visceral sensitivity index (VSI), examined a UK population...

BACKGROUND The method of carpal tunnel syndrome (CTS) treatment depends on the severity of the symptoms. It is generally accepted that patients with mild and moderate CTS may be referred for conservative treatment while surgical treatment is recommended in patients with severe symptoms. The conclusions drawn on the basis of our study results should facilitate predicting treatment outcomes in pa...

BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) has a range of aetiological origins which are associated with a number of disruptions in neuropsychological functioning. This study aimed to examine how low birth weight, a proxy measure for a range of environmental complications during gestation, predicted ADHD symptom severity in preschool-aged children indirectly via neuropsychologic...

BACKGROUND AND OBJECTIVES Although several studies have found that the burden of symptoms in patients who are on maintenance hemodialysis is substantial, little is known about renal providers' awareness of these symptoms. The aim of this study was to assess renal provider recognition of symptoms and their severity in hemodialysis patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The Dia...

BACKGROUND The aim of this study was to investigate the correlation between incidence of lower urinary tract symptoms and erectile dysfunction in men aged ≥50 years. MATERIAL AND METHODS A cross-sectional study was performed in 1644 men aged >50 years in Beijing. The International Index of Erectile Function (IIEF)-5 and International Prostate Symptom Score were recorded for each patient. Pear...

This study examined the symptom response trajectories for 225 children and youth throughout a period of residential treatment. With the 10-item Conners' Global Index (CGI) as the primary outcome measure, assessments were completed on a bi-weekly basis during the average 4 month stay within the youth's residential treatment. Clients demonstrated an ongoing reduction of symptoms, and the severity...

BACKGROUND To determine the clinimetric properties of two questionnaires assessing symptoms (Symptom Severity Scale) and physical functioning (hand and finger function subscale of the AIMS2) in a Dutch primary care population. METHODS The first 84 participants in a 1-year follow-up study on the diagnosis and prognosis of hand and wrist problems completed the Symptom Severity Scale and the han...