نتایج جستجو برای: sympathetic system
تعداد نتایج: 2250006 فیلتر نتایج به سال:
We wish to comment on the article by de Champlain and Ameringen (Circ Res 31:617-628, 1972) in which they implicate the involvement of the peripheral sympathetic nervous system in the etiology of deoxycorticosterone (DOCA)-saline hypertension. In the Discussion of their article, the work of Clarke et al. (Life Sci [I] 9:1097-1108, 1970) has been misquoted. Contrary to the authors' impression, w...
Heart failure (HF) is a syndrome characterized by upregulation of the sympathetic nervous system and abnormal responsiveness of the parasympathetic nervous system. Studies in the 1980s and 1990s demonstrated that inhibition of the renin-angiotensin-aldosterone system with angiotensin-converting enzyme inhibitors improved symptoms and mortality in HF resulting from systolic dysfunction, thus pro...
The sympathetic nervous system, via postganglionic innervation of blood vessels and the heart, is an important determinant of cardiovascular function. The mechanisms underlying sympathetic innervation of targets are not fully understood. This study tests the hypothesis that target-derived vascular endothelial growth factor (VEGF) promotes sympathetic innervation of blood vessels. Western blot a...
There is growing evidence that essential hypertension is commonly neurogenic and is initiated and sustained by sympathetic nervous system overactivity. Potential mechanisms include increased central sympathetic outflow, altered norepinephrine (NE) neuronal reuptake, diminished arterial baroreflex dampening of sympathetic nerve traffic, and sympathetic neuromodulation by angiotensin II. To addre...
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