Topical foscarnet (PFA) and acyclovir (ACV) were compared in the dorsal cutaneous guinea pig model of herpes simplex virus type 1 infection. The relative order of efficacy was PFA cream greater than ACV cream greater than ACV ointment. In vitro studies demonstrated that PFA and ACV formulated in cream vehicles penetrated through guinea pig skin 7- to 10-fold faster than did ACV in ointment.

The fly pharyngeal sense organs lie at the transition between external and internal nutrient-sensing mechanisms. Here we investigate the function of pharyngeal sweet gustatory receptor neurons, demonstrating that they express a subset of the nine previously identified sweet receptors and respond to stimulation with a panel of sweet compounds. We show that pox-neuro (poxn) mutants lacking taste ...

Sweet and umami (the taste of monosodium glutamate) are the main attractive taste modalities in humans. T1Rs are candidate mammalian taste receptors that combine to assemble two heteromeric G-protein-coupled receptor complexes: T1R1+3, an umami sensor, and T1R2+3, a sweet receptor. We now report the behavioral and physiological characterization of T1R1, T1R2, and T1R3 knockout mice. We demonstr...

The research for suggesting an ice cream for a diabetic patient is carried out in data mining by using clustering and mapping between the data for ice cream and diabetic patients. Here, using MFCA, which is proposed and explained in this paper, does mapping of ice cream dataset with diabetic patient dataset. The results obtained from MCFA algorithm and the new extended MCF algorithm are explain...

AIMS To assess Sweet Talk, a text-messaging support system designed to enhance self-efficacy, facilitate uptake of intensive insulin therapy and improve glycaemic control in paediatric patients with Type 1 diabetes. METHODS One hundred and twenty-six patients fulfilled the eligibility criteria; Type 1 diabetes for > 1 year, on conventional insulin therapy, aged 8-18 years. Ninety-two patients...

Introduction: Oral lichen planus (OLP) is a common chronic mucocutaneous disease. Patients with atrophic and erosive types of OLP often have symptoms of soreness, and require proper treatment. The main treatment for OLP has been the administration of topical or systemic corticosteroids. The objective of this study was to compare the efficacy of adcortyl cream (triamcinolone acetonide in orabase...

in order to evaluate intercropping of soybean (glycine max l. cv. jk) with sweet basil (ocimum basilicum l.) and borage (borago officinalis l.) with weed interference, an experiment was performed in randomized complete block design with 12 treatments and three replications at a field located 10 km of shirvan during year of 2011. the treatments were included 75% soybean: 25%sweet basil, 50%soybe...

a topical o/w cream containing tretinoin microspheres was prepared. gelatin microspheres of tretinoin were prepared using coacervation method. these microspheres contained about 50% w/w tretinoin. the particle size range of microspheres was between 90-150 m m. in vitro drug release from microspheres and a cream formulation was studied. it was shown that drug release from microspheres followed h...

Application of power ultrasound to Food freezing is a relatively new subject, cavitations is the most significant power which can not only lead to the production of gas bubbles in ice ream but also the occurrence of micro streaming, also it can promote ice nucleation to accelerate the heat and mass transfer process accompanying the freeze process. In this work ice cream freezing process time af...

Morphological studies showed that tree shape in Bitter sweet orange and Yuma citrange was spheroid with spreading growth habit and wide branch angle. Leaves were simple with dark green color, medium size and brevipetiolate in Sour orange while Yuma citrange had trifoliate leaves with medium and green color. Bitter sweet orange had the highest leaf lamina length (10.4 mm) than other rootstocks. ...