abstract study design . a retrospective radiographic review was undertaken in patients treated for ais. objectives. to determine the most important preoperative factors that affect on postoperative junctional kyphosis complication. methods sagittal spine profilewere measured on the standing radiographs before, after and in the last follow-up visit of the operated patients for ais. the following...

In this commentary, we will provide a high-level introduction into LC-MS product characterization methodologies deployed throughout biopharmaceutical development. The ICH guidelines for early and late phase filings is broad so that it applicable to diverse biotherapeutic products in the clinic industry pipelines. This commentary meant address areas of protein primary sequence confirmation varia...

PURPOSE The purpose of this study was to identify the influence of pelvic incidence (PI) on spinopelvic parameters in patients with degenerative lumbar scoliosis (DLS) and compare them with those of a normal population. METHODS There were two groups in this study. One group was composed by 136 patients with DLS and another was composed by 120 participants free of spinal disease. In each group...

Background Previous studies on the correlation between cervical sagittal balance with improvement in quality of life showed significant results only for parameters of the anterior translation of the cervical spine (such as C2-C7 SVA). Objective We test whether a new parameter, cervicothoracic lordosis, can predict clinical success in this type of surgery. Methods The focused group involved ...

Although human diseases of retrotransposition-derived etiology have been documented, retrotransposon RNA expression and the occurrence of retrotransposition events in the human oocyte are not studied. We investigated the RNA expression of L1 and HERV-K10 retrotransposons in human oocytes by RT-PCR analysis with designed primers. Using denucleated germinal vesicles (GVs), we detected RT-PCR prod...

This paper describes our submission for the CoNLL 2013 Shared Task, which aims to to improve the detection and correction of the five most common grammatical error types in English text written by non-native speakers. Our system concentrates only on two of them; it employs machine learning classifiers for the ArtOrDet-, and a fully deterministic rule based workflow for the SVA error type.

BACKGROUND CONTEXT Lumbar spinal stenosis (LSS) is the most common lumbar degenerative disease, and sagittal imbalance is uncommon. Forward-bending posture, which is primarily caused by buckling of the ligamentum flavum, may be improved via simple decompression surgery. PURPOSE The objectives of this study were to identify the risk factors for sagittal imbalance and to describe the outcomes o...

STUDY DESIGN A retrospective study of surgical outcomes of adult spinal deformity (ASD) cases. OBJECTIVE The aim of the study was to investigate the effects of high T1 slope (T1S) on surgical outcomes in patients with ASD. SUMMARY OF BACKGROUND DATA Few studies have evaluated the surgical outcomes of patients with ASD with cervical deformities. METHODS Eighty-eight patients with ASD who u...