PAMAM dendrimers of generations G2-G3 as well as a partially substituted derivative of generation G4 and a low-molecular-weight tricyclic ligand 4 were used to bind Pd(0) nanoparticles. The obtained adducts were tested as catalysts for C-C cross-coupling reactions, such as the Suzuki-Miyaura, Hiyama, Heck and Sonogashira reaction. The highest yields of the coupling product, diphenylacetylene, w...

Abstract Here we report an efficient and short total synthesis of bulgarein ( 1 ), a natural compound from Bulgaria inquinans with cytotoxic activity. Key steps in the are Suzuki‐Miyaura coupling reaction two substituted naphthalene derivates followed by polyphosphoric acid (PPA) mediated condensation to form benzo[ j ]fluoranthene skeleton. Bulgarein ) was achieved over 4 overall yield 25 %.

DNA-encoded synthesis can generate vastly diverse screening libraries of arbitrarily complex molecules as long as chemical reaction conditions do not compromise DNA's informational integrity, a fundamental constraint that "DNA-compatible" reaction development does not presently address. We devised DNA-encoded reaction rehearsal, an integrated analysis of reaction yield and impact on DNA, to acq...

Suppose that  is a finite group. Then the set of all prime divisors of  is denoted by  and the set of element orders of  is denoted by . Suppose that . Then the number of elements of order  in  is denoted by  and the sizes of the set of elements with the same order is denoted by ; that is, . In this paper, we prove that if  is a group such that , where , then . Here  denotes the family of Suzuk...

Pseudo-benzylic substitution is an important reaction in the ferrocene series, especially to obtain ligands for catalysis. Herein, we described new reactions conditions, using fluorinated alcohols as both solvent and promoter, able deliver iodoferrocene derivatives faster than classical solvents. Various N, O, P C-nucleophiles were found compatible with this transformation which occurs full ret...

A regioselective Suzuki–Miyaura cross-coupling reaction on 3 0,5 0-dibromo pyridinium N-(2 0-azinyl)aminides is reported. A series of 3 0-aryl(or heteroaryl)-5 0-bromo-pyridinium N-(2 0-pirazinyl)aminides were obtained in good yields. Two isomeric 3 0,5 0diaryl pyridinium N-(2 0-azinyl)aminides were also prepared. 2006 Elsevier Ltd. All rights reserved. Functionalization of heterocycles through...

In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronate esters in good to excellent yields. These compounds were further utilized to build peptoid analogs via an Ugi four-component reaction (Ugi-4CR) u...

Abstract Bimetallic proline-containing composites Pd–Ni(Co, Cu, Fe)–Pro/Al 2 O 3 , due to the synergistic effect, exhibit high catalytic activity in Suzuki reaction aqueous media, which makes it possible reduce amount of expensive Pd 10 –2 mol %. New catalysts are easily regenerated from mixture and can be reused up 5 times without losing activity.

Herein, we report the one-pot synthesis of an electron-poor nanographene containing dicarboximide groups at the corners. We efficiently combined palladium-catalyzed Suzuki-Miyaura cross-coupling and dehydrohalogenation to synthesize an extended two-dimensional π-scaffold of defined size in a single chemical operation starting from N-(2,6-diisopropylphenyl)-4,5-dibromo-1,8-naphthalimide and a te...

Variously substituted 1,3-diarylisobenzofurans have been regiospecifically prepared via palladium- and rhodium-catalysed reaction of functionalised boronic acids onto o-acylbenzaldehydes. Rhodium catalysis has furthermore been improved using microwave activation. Thus, isobenzofurans containing aryl groups substituted by halogens, unprotected amine, alcohol and even aldehyde groups, have been o...