Objective To analyze cases of recurrent glioblastoma subjected to reoperation at a Brazilian public healthcare service. Methods A total of 39 patients subjected to reoperation for recurrent glioblastoma at the Department of Neurosurgery, São Paulo Hospital, Federal University of São Paulo, from January 2000 to December 2013 were retrospectively analyzed. Results The median overall survival ...

There are now hundreds of empirical studies that have confirmed the main predictions of transaction cost economics regarding the alignment of transactions with governance 2001) have noted, there are very few empirical studies that demonstrate the impact of this economizing alignment on performance. Some critics of the theory have noted that in order for the theory to be of relevance to other or...

Survivor of a ship ground in polar regions may have to wait more than five days before being rescued. Therefore, the purpose of this study was to explore cognitive performance during prolonged cold exposure. Core temperature (T c) and cognitive test battery (CTB) performance data were collected from eight participants during 24 hours of cold exposure (7.5°C ambient air temperature). Participant...

Survival analysis is concerned with nding models to predict the survival of patients or to assess the eecacy of a clinical treatment. A key part of the model-building process is the selection of the predictor variables. It is standard to use a stepwise procedure guided by a series of signiicance tests to select a single model, and then to make inference conditionally on the selected model. Howe...

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The Cox proportional hazards model is widely used for analyzing associations between risk factors and occurrences of events. One of the essential requirements of defining Cox proportional hazards model is the choice of a unique and well-defined time scale. Two time scales are generally used in epidemiological studies: time-on-study and chronological age. The former is the most frequently used t...

rhabdomyosarcoma (rms) is the most frequent soft tissue sarcoma in children. the aim of study was to retrospectively review the treatment results of childhood rhabdomyosarcoma and identify prognostic factors. 60 children with rhabdomyosarcoma treated between 1996 and 2002 in shafa hospital were reviewed. the data were analyzed for clinico-epidemiological factors. age, gender, race, histology ty...

background and objectives: retinoblastoma is the most common intraocular pediatric malignancy. angiogenic factor expression such as vegf (vascular endothelial growth factor) in retinoblastoma can be confirmatory angiogenic potential of this tumor. this study was performed to determine the role of angiogenesis in local invasion of retinoblastoma and its correlation with patients’ survival. mater...